ChemicalBook > CAS DataBase List > 2-NITRO-3-AMINO-4-METHYLBENZOIC ACID

2-NITRO-3-AMINO-4-METHYLBENZOIC ACID

Product Name
2-NITRO-3-AMINO-4-METHYLBENZOIC ACID
CAS No.
37901-90-9
Chemical Name
2-NITRO-3-AMINO-4-METHYLBENZOIC ACID
Synonyms
2-NITRO-3-AMINO-4-METHYLBENZOIC ACID;3-AMINO-4-METHYL-2-NITROBENZOIC ACID;Benzoic acid, 3-amino-4-methyl-2-nitro-
CBNumber
CB4282433
Molecular Formula
C8H8N2O4
Formula Weight
196.16
MOL File
37901-90-9.mol
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2-NITRO-3-AMINO-4-METHYLBENZOIC ACID Property

Boiling point:
444.8±45.0 °C(Predicted)
Density 
1.482±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
2.52±0.25(Predicted)
InChI
InChI=1S/C8H8N2O4/c1-4-2-3-5(8(11)12)7(6(4)9)10(13)14/h2-3H,9H2,1H3,(H,11,12)
InChIKey
JLWAVVAJFWDXEF-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(C)C(N)=C1[N+]([O-])=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0010248
Product name
3-AMINO-4-METHYL-2-NITRO BENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$504.92
Updated
2021/12/16
Crysdot
Product number
CD12077274
Product name
3-Amino-4-methyl-2-nitrobenzoicacid
Purity
95+%
Packaging
250mg
Price
$88
Updated
2021/12/16
Crysdot
Product number
CD12077274
Product name
3-Amino-4-methyl-2-nitrobenzoicacid
Purity
95+%
Packaging
1g
Price
$219
Updated
2021/12/16
Crysdot
Product number
CD12077274
Product name
3-Amino-4-methyl-2-nitrobenzoicacid
Purity
95+%
Packaging
5g
Price
$876
Updated
2021/12/16
Chemcia Scientific
Product number
BB20-4530
Product name
3-Amino-4-methyl-2-nitro-benzoicacid
Purity
＞97%
Packaging
5G
Price
$995
Updated
2021/12/16
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2-NITRO-3-AMINO-4-METHYLBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

7356-52-7

37901-90-9

General procedure for the synthesis of 3-amino-4-methyl-2-nitrobenzoic acid from 3-acetamido-4-methyl-2-nitrobenzoic acid: To a solution of 3-acetamido-4-methyl-2-nitrobenzoic acid (79 g, 0.33 mol, 1.0 eq.) in dioxane (400 mL) was added dropwise 6N hydrochloric acid (200 mL). The reaction mixture was heated under reflux conditions overnight. Upon completion of the reaction, it was extracted with ethyl acetate (200 mL × 3). The organic phases were combined and dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure. The resulting solid was ground with mixed solvents (petroleum ether/ethyl acetate = 10/1, v/v) and filtered to give 3-amino-4-methyl-2-nitrobenzoic acid (60 g, 92.7% yield).

References

[1] Patent: WO2018/218070, 2018, A2. Location in patent: Page/Page column 181; 182
[2] Patent: WO2015/27222, 2015, A2. Location in patent: Paragraph 0279
[3] Patent: WO2007/76092, 2007, A2. Location in patent: Page/Page column 71
[4] Patent: US2004/167194, 2004, A1. Location in patent: Page 23

2-NITRO-3-AMINO-4-METHYLBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-NITRO-3-AMINO-4-METHYLBENZOIC ACID Suppliers

China 25 Germany 1 Russia 1 United States 2 Global 29
Quzhou AMK BioTech Co., Ltd
Tel
0570-3081766 18357083060
Fax
0570-3072337
Email
sales@qzamkbio.com
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China
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1046
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
ProdList
42934
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64
Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
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4705
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70
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
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China
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16679
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SuZhou ShiYa Biopharmaceuticals, Inc.
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0512-0512-52358471 17715136450
Fax
05125235 6881
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sales@shiyabiopharm.com
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China
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12127
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Sichuan BaiPeng Biotechnology Co., Ltd.
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028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
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China
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9997
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Cool Pharm, Ltd
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021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
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China
ProdList
12878
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58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
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China
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19778
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58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
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China
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52846
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37901-90-9, 2-NITRO-3-AMINO-4-METHYLBENZOIC ACIDRelated Search:

3-Amino-3-(4-methoxyphenyl)propionic acid 3-PYRIDINAMINE, 6-(1-METHYLETHYL)- 3-AMINO-5-HYDROXYBENZOIC ACID 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE 2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID 3,5-BIS(ACETYLAMINO)-4-METHYL-2-NITRO-BENZOIC ACID 2-NITRO-3-AMINO-4-METHYLBENZOIC ACID 5-BROMO-2-NITRO-3-AMINO-4-METHYLBENZOIC ACID 2-NITRO-5-AMINO-4-METHYLBENZOIC ACID 2-NITRO-3,5-DIAMINO-4-METHYL-BENZOIC ACID 5-BROMO-2-NITRO-3-ACETYL-AMINO-4-METHYLBENZOIC ACID 2-NITRO-5-THIOCYANATO-3-ACETYLAMINO-4-METHYLBENZOIC ACID 5-CHLORO-2-NITRO-3-ACETYLAMINO-4-METHYLBENZOIC ACID 2,6-DINITRO-3,5-DIACETYLAMINO-4-METHYLBENZOIC ACID 2,6-DINITRO-3,5-DIAMINO-4-METHYLBENZOIC ACID 2-NITRO-5-AMINO-3-(ACETYL-AMINO)-4-METHYLBENZOIC ACID 5-CHLORO-2-NITRO-3-AMINO-4-METHYLBENZOIC ACID

  • 3-AMINO-4-METHYL-2-NITROBENZOIC ACID
  • 2-NITRO-3-AMINO-4-METHYLBENZOIC ACID
  • Benzoic acid, 3-amino-4-methyl-2-nitro-
  • 37901-90-9
  • API intermediates