Ethyl methanesulfonate
- Product Name
- Ethyl methanesulfonate
- CAS No.
- 62-50-0
- Chemical Name
- Ethyl methanesulfonate
- Synonyms
- EMS;ETHYL MESYLATE;METHANESULFONIC ACID ETHYL ESTER;CB 1528;Ethyl methansulfonate;ETHYL METHANESULPHONATE;ethylesterofmethylsulfonicacid;ethylesterofmethanesulfonicacid;ethylesterofmethylsulphonicacid;ethylesterofmethanesulphonicacid
- CBNumber
- CB4292779
- Molecular Formula
- C3H8O3S
- Formula Weight
- 124.16
- MOL File
- 62-50-0.mol
Ethyl methanesulfonate Property
- Melting point:
- <25 °C
- Boiling point:
- 85-86 °C/10 mmHg (lit.)
- Density
- 1.206 g/mL at 20 °C
- vapor pressure
- 0.27 hPa (25 °C)
- refractive index
- n20/D 1.418(lit.)
- Flash point:
- 100 °C
- storage temp.
- 2-8°C
- solubility
- 50-100g/l
- form
- liquid
- color
- Colourless to Pale Yellow
- Water Solubility
- Miscible with water.
- Sensitive
- Moisture Sensitive
- Merck
- 14,3827
- BRN
- 773969
- Stability:
- Stable. Combustible. Incompatible with water, alkalies, oxidizing agents.
- InChIKey
- PLUBXMRUUVWRLT-UHFFFAOYSA-N
- CAS DataBase Reference
- 62-50-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Methanesulfonic acid, ethyl ester(62-50-0)
- IARC
- 2B (Vol. 7, Sup 7) 1987
- EPA Substance Registry System
- Ethyl methanesulfonate (62-50-0)
Safety
- Hazard Codes
- T
- Risk Statements
- 46-22-40-36/37/38-45
- Safety Statements
- 53-23-36/37/39-45-36/37-37/39-26
- RIDADR
- 2810
- WGK Germany
- 3
- RTECS
- PB2100000
- F
- 10-21
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29041000
- Hazardous Substances Data
- 62-50-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H340May cause genetic defects
H350May cause cancer
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M0880
- Product name
- Ethyl methanesulfonate
- Purity
- liquid
- Packaging
- 1g
- Price
- $43.4
- Updated
- 2024/03/01
- Product number
- 8.20774
- Product name
- Ethyl methanesulfonate
- Purity
- for synthesis
- Packaging
- 5ml
- Price
- $47
- Updated
- 2024/03/01
- Product number
- 8.20774
- Product name
- Ethyl methanesulfonate
- Purity
- for synthesis
- Packaging
- 25mL
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 72945
- Product name
- Ethyl methanesulfonate
- Purity
- certified reference material, TraceCERT
- Packaging
- 120mg
- Price
- $131
- Updated
- 2024/03/01
- Product number
- M0607
- Product name
- Ethyl Methanesulfonate
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $51
- Updated
- 2024/03/01
Ethyl methanesulfonate Chemical Properties,Usage,Production
Chemical Properties
colourless liquid
Chemical Properties
Ethyl methane sulfonate is a clear liquid.
Uses
Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Uses
Experimentally as mutagen, teratogen and brain carcinogen.
Definition
ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
General Description
Clear colorless liquid. Denser than water.
Air & Water Reactions
Water soluble.
Reactivity Profile
Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .
Fire Hazard
Ethyl methanesulfonate is combustible.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplas tigenic, tumorigenic, and teratogenic data. Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES and ESTERS.
Potential Exposure
Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible human male contraceptive. Also considered as a reversible male hemosterilant for insects and mammalian pests.
Carcinogenicity
Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.
Incompatibilities
Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with moisture may cause hydrolysis or other forms of decomposition
Ethyl methanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl methanesulfonate manufacturers
- Product
- Ethyl methanesulfonate 62-50-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-05-09
- Product
- Ethyl methanesulfonate 62-50-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-25
- Product
- Ethyl Methanesulfonate 62-50-0
- Price
- US $10.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2024-08-08