4-CHLORO-3-FLUOROPHENYLACETIC ACID

Product Name: 4-CHLORO-3-FLUOROPHENYLACETIC ACID
CAS No.: 883500-51-4
Chemical Name: 4-CHLORO-3-FLUOROPHENYLACETIC ACID
Synonyms: Acid 3-fluoro-4-chloro;4-Chloro-3-fluorphenylaceticacid;3-fluoro-4-chlorophenylacetic acid;4-CHLORO-3-FLUOROPHENYLACETIC ACID;4-Chloro-3-fluorobenzeneacetic acid;2-(4-Chloro-3-fluorophenyl)acec Acid;4-Chloro-3-fluorophenylaceticacid,97%;Benzeneacetic acid, 4-chloro-3-fluoro-
CBNumber: CB4293004
Molecular Formula: C8H6ClFO2
Formula Weight: 188.58
MOL File: Mol file

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4-CHLORO-3-FLUOROPHENYLACETIC ACID Property

Melting point:: 88-91℃
Boiling point:: 293.1±25.0 °C(Predicted)
Density: 1.417±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.97±0.10(Predicted)
Appearance: White to off-white Solid

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Safety

Hazard Codes: Xi,E
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
Hazard Note: Irritant
HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C584713
Product name: 4-Chloro-3-fluorophenylaceticacid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: C584713
Product name: 4-Chloro-3-fluorophenylaceticacid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC63966
Product name: 4-Chloro-3-fluorophenylacetic acid
Packaging: 5G
Price: $50
Updated: 2021/12/16

Matrix Scientific

Product number: 009488
Product name: 4-Chloro-3-fluorophenylacetic acid
Purity: 98%
Packaging: 5g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: PC9429
Product name: 4-Chloro-3-fluorophenylaceticacid
Packaging: 5g
Price: $50
Updated: 2021/12/16

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4-CHLORO-3-FLUOROPHENYLACETIC ACID Chemical Properties,Usage,Production

Synthesis

251570-03-3

883500-51-4

General procedure for the synthesis of 4-chloro-3-fluorophenylacetic acid from 3-fluoro-4-chlorophenylacetonitrile: A mixture of 3-fluoro-4-chlorophenylacetonitrile (7.8 g, 0.046 mol), water (7.5 mL), concentrated sulfuric acid (7.5 mL) and acetic acid (7.5 mL) was heated and refluxed for 2 hours. After the reaction was completed, the mixture was cooled to room temperature and then slowly poured into ice water. The precipitated solid product was collected by filtration and washed with ether to yield 4-chloro-3-fluorophenylacetic acid (6.8 g, 79% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 3.64 (s, 2H), 7.14 (ddd, J = 0.6, 2.1, 8.2 Hz, 1H), 7.34 (dd, J = 2.1, 10.6 Hz, 1H), 7.52 (t, J = 8.1 Hz, 1H). Mass spectrum (ESI-) m/z: 187 [M-H]-.

References

[1] Patent: WO2010/31, 2010, A1. Location in patent: Page/Page column 55
[2] Patent: WO2010/32, 2010, A1. Location in patent: Page/Page column 54
[3] Patent: WO2010/30, 2010, A1. Location in patent: Page/Page column 48

4-CHLORO-3-FLUOROPHENYLACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-3-FLUOROPHENYLACETIC ACID Suppliers

China 69 Germany 1 India 1 United Kingdom 7 United States 8 Global 86

Alfa Aesar

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Wuhan Arike Technology Co., Ltd.

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9ding chemical ( Shanghai) Limited

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View Lastest Price from 4-CHLORO-3-FLUOROPHENYLACETIC ACID manufacturers

Career Henan Chemical Co

Product: 4-CHLORO-3-FLUOROPHENYLACETIC ACID 883500-51-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

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