ChemicalBook > CAS DataBase List > 2,3-DIFLUORO-4-METHOXYBENZOIC ACID

2,3-DIFLUORO-4-METHOXYBENZOIC ACID

Product Name: 2,3-DIFLUORO-4-METHOXYBENZOIC ACID
CAS No.: 773873-26-0
Chemical Name: 2,3-DIFLUORO-4-METHOXYBENZOIC ACID
Synonyms: 2,3-Difluoro-6-methoxybenzoic acid;2,3-Difluoro-4-methoxylbenzoic acid;Benzoic acid, 2,3-difluoro-6-methoxy-
CBNumber: CB4297305
Molecular Formula: C8H6F2O3
Formula Weight: 188.13
MOL File: 773873-26-0.mol

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2,3-DIFLUORO-4-METHOXYBENZOIC ACID Property

Melting point:: 126-129°C
Boiling point:: 275.0±35.0 °C(Predicted)
Density: 1.399±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.82±0.10(Predicted)

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2918999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: D452060
Product name: 2,3-Difluoro-6-methoxybenzoicAcid
Packaging: 500mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD67545
Product name: 2,3-Difluoro-6-methoxybenzoic acid
Packaging: 10g
Price: $115
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD67545
Product name: 2,3-Difluoro-6-methoxybenzoic acid
Packaging: 5G
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 116758
Product name: 2,3-Difluoro-6-methoxybenzoicacid
Packaging: 5g
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: X2810
Product name: 2,3-Difluoro-6-methoxybenzoicacid
Packaging: 5g
Price: $189
Updated: 2021/12/16

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2,3-DIFLUORO-4-METHOXYBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

187543-87-9

773873-26-0

General procedure for the synthesis of 2,3-difluoro-6-methoxybenzoic acid from 2,3-difluoro-6-methoxybenzaldehyde: 1. Preparation of reaction system: 2,3-difluoro-6-methoxybenzaldehyde (0.5 g, 2.91 mmol) was suspended in potassium hydroxide solution (3 g KOH dissolved in 20 ml of water). 2. Oxidizing reaction: hydrogen peroxide solution (27.5% w/w, 4 ml) was added to the above suspension, followed by heating the reaction at 70°C for 2 hours. 3. Acidification: after completion of the reaction, the reaction mixture was acidified to pH 2 with concentrated hydrochloric acid. 4. Extractive separation: the acidified reaction mixture was washed with ethyl acetate. 5. Drying and concentration: the organic phases were combined, dried with anhydrous magnesium sulfate, filtered and the solvent was evaporated in vacuum. 6. Purification: Further purification by azeotropy with toluene afforded 2,3-difluoro-6-methoxybenzoic acid as a white solid (500 mg, 91% yield). Remarks: LC/MS analysis showed a retention time of 12.08 min and no molecular ion peak was observed.

References

[1] Patent: WO2006/77414, 2006, A1. Location in patent: Page/Page column 148
[2] Patent: CN105523921, 2016, A. Location in patent: Paragraph 0014; 0015; 0016

2,3-DIFLUORO-4-METHOXYBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DIFLUORO-4-METHOXYBENZOIC ACID Suppliers

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View Lastest Price from 2,3-DIFLUORO-4-METHOXYBENZOIC ACID manufacturers

Career Henan Chemical Co

Product: 2,3-DIFLUORO-4-METHOXYBENZOIC ACID 773873-26-0
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

773873-26-0, 2,3-DIFLUORO-4-METHOXYBENZOIC ACIDRelated Search:

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