HuangjiangSu A
- Product Name
- HuangjiangSu A
- CAS No.
- 1026020-27-8
- Chemical Name
- HuangjiangSu A
- Synonyms
- HuangjiangSu A;β-D-Glucopyranoside, (3β,25R)-26-(β-D-glucopyranosyloxy)furosta-5,20(22)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;(3beta,25R)-26-(beta-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranoside
- CBNumber
- CB43037627
- Molecular Formula
- C51H82O22
- Formula Weight
- 1047.2
- MOL File
- 1026020-27-8.mol
HuangjiangSu A Property
- Melting point:
- 274-276 °C
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 12?+-.0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- 300434
- Product name
- HuangjiangSuA
- Packaging
- 20mg
- Price
- $722
- Updated
- 2021/12/16
- Product number
- orb259301
- Product name
- HuangjiangSuA
- Purity
- 98%
- Packaging
- 5mg
- Price
- $923.1
- Updated
- 2021/12/16
- Product number
- CS-0032616
- Product name
- HuangjiangsuA
- Packaging
- 5mg
- Price
- $1429
- Updated
- 2021/12/16
- Product number
- CS-0032616
- Product name
- HuangjiangsuA
- Packaging
- 1mg
- Price
- $476
- Updated
- 2021/12/16
HuangjiangSu A Chemical Properties,Usage,Production
Description
Huangjiangsu A is a natural active ingredient found in many plants such as Dioscorea villosa and Polygonatum multiflorum. It belongs to the steroidal saponin class of compounds. Huangjiangsu A is not cytotoxic, and treatment of HepG2 cells with it prior to exposure to H2O2 was effective in increasing cell viability in a concentration-dependent manner. In addition, 50 μM of Huangjiangsu A, pseudoprotodioscin, methyl protobioside, protodioscin, and protodeltonin increased GSH levels and reduced intracellular ROS production, thereby counteracting H2O2-induced injury. Thus, Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation, and is expected to be a potential drug for the treatment of liver diseases[1-2].
References
[1] MAQSOOD A SIDDIQUI. Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells.[J]. Frontiers in Pharmacology, 2018. DOI:10.3389/fphar.2018.00797.
[2] LILI GVAZAVA . New furostanol glycosides from Polygonatum multiflorum (L.) All.[J]. Natural Product Research, 2019. DOI:10.1080/14786419.2018.1431628.
HuangjiangSu A Preparation Products And Raw materials
Raw materials
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