ChemicalBook > CAS DataBase List > Halobetasol propionate

Halobetasol propionate

Product Name
Halobetasol propionate
CAS No.
66852-54-8
Chemical Name
Halobetasol propionate
Synonyms
CGP-14458;BMY-30056;Ultravate;Miracorten;ulobetasol propionate;Uiobetasol Propionate;Halobatasol Proionate;HALOBETASOL PROPIONATE;HalobetasolPropionate>Halobetasol Propionate (200 mg)
CBNumber
CB4305095
Molecular Formula
C25H31ClF2O5
Formula Weight
484.96
MOL File
66852-54-8.mol
More
Less

Halobetasol propionate Property

Melting point:
213-215°C
Boiling point:
570.7±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.55±0.70(Predicted)
color 
White to Off-White
InChIKey
BDSYKGHYMJNPAB-QNGYMBKVNA-N
SMILES
O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|
CAS DataBase Reference
66852-54-8(CAS DataBase Reference)
More
Less

Safety

HS Code 
2937220000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1302906
Product name
Halobetasol propionate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200MG
Price
$174.4
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
10mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
50mg
Price
$169
Updated
2024/03/01
More
Less

Halobetasol propionate Chemical Properties,Usage,Production

Description

Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis.  It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis.

Chemical Properties

White Solid

Originator

Ciba-Geigy (Switzerland)

Uses

Halobetasol propionate is a corticosteroid (cortisone-like medicine or steroid). As an anti-inflammatory drug, halobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis.This medicine is available only with doctor's prescription.

Definition

ChEBI: Ulobetasol propionate is a corticosteroid hormone.

brand name

Ultravate (Westwood-Squibb).

Halobetasol propionate Preparation Products And Raw materials

Raw materials

Acetylacetone Methanesulfonyl chloride Lithium chloride

Preparation Products

More
Less

Halobetasol propionate Suppliers

Brazil 1 Canada 1 China 197 Czech Republic 1 Europe 3 Germany 1 India 60 Israel 4 Italy 4 Japan 1 Malaysia 3 Philippines 1 Portugal 1 United Arab Emirates 1 United Kingdom 8 United States 25 Global 312
WUHAN MEIAN BIOMEDICINE TECHNOLOGY Co., Ltd，
Tel
15377551262
Email
180953430@qq.com
Country
China
ProdList
166
Advantage
58
Changsha Qisheng Heyan Medical Technology Co., LTD
Tel
18684929597
Email
527907673@qq.com
Country
China
ProdList
193
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
Nanjing MeiBo Biological Technology Co., Ltd.
Tel
025-58619198
Fax
025-58619197
Email
sales@mbbio.com
Country
China
ProdList
319
Advantage
60
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
Country
China
ProdList
977
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
VOT INTERNATIONAL BUSINESS CO.,LTD
Tel
0536-2456718
Fax
0536-8231856
Country
China
ProdList
226
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9972
Advantage
58
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
990
Advantage
55
Shanghai Shanyuan pharmaceutical technology co., LTD
Tel
021-31761238 13167072949
Fax
021-31761238
Email
3146446224@qq.com
Country
China
ProdList
1609
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
Chengdu HuaNa Chemicals Co., Ltd.
Tel
028-86612776; 13699069380
Fax
-
Email
515238037@qq.com
Country
China
ProdList
963
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
025-57798860
Email
sales@njromanme.com
Country
China
ProdList
4534
Advantage
58
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5115
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@QQ.COM
Country
China
ProdList
1891
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6120
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-59402396 13419635609
Fax
027-83989310
Email
13419635609@163.com
Country
China
ProdList
1993
Advantage
55
Guangzhou Kafen Biotech Co.,Ltd
Tel
18029243487 2355327168
Fax
020-31121510
Email
gy@yccreate.com
Country
China
ProdList
4753
Advantage
55
Wuhan Runzeweiye Technology Co., Ltd.
Tel
027-50779735 15172337137
Fax
027-50779735
Email
runzeweiye999@163.com
Country
China
ProdList
734
Advantage
55
Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3979
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9974
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4887
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9293
Advantage
58
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ：2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6504
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
XinYao(Shenzhen) Biological Technology Co., Ltd.
Tel
0755-89880280
Fax
0755-89880280
Email
3004662104@qq.com
Country
China
ProdList
1830
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187 13917602471
Fax
021-60345187
Email
lzz841106@aliyun.com
Country
China
ProdList
9908
Advantage
58
More
Less

View Lastest Price from Halobetasol propionate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500
Release date
2023-07-31
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-01
Hebei Mojin Biotechnology Co., Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-05-19

66852-54-8, Halobetasol propionateRelated Search:

BENORILATE Calcium Propionate LINALYL PROPIONATE Clobetasol propionate Vitamin D3 Diflorasone Dilauryl thiodipropionate Ufenniso Difluorochloromethane Clobetasol 3-Chloropropyl acetate 1-ACETOXY-3-CHLOROACETONE 1-Chlorohexadecane Ethanone, 2-chloro-1-cyclopentyl- (9CI) 4-Chloro-2-methyl-2-butanol HALOBETASOL Halobetasol propionate

  • ulobetasol propionate
  • HALOBETASOL PROPIONATE
  • BMY-30056
  • CGP-14458
  • Uiobetasol Propionate
  • Ultravate
  • 21-chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
  • 6 alpha-fluoroclobetasol 17-propionate
  • (6α，11β，16β)-21-Chloro-6，9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1，4-diene-3，20-dione
  • Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6-alpha,11-beta,16-beta)
  • Ulobetasol (Halobetasol)Propionate
  • Pregna-1,4-diene-3,20-dione,21-chloro-6,9-difluoro-11-hydroxy-16-Methyl-17-(1-oxopropoxy)-, (6a,11b,16b)-
  • Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)-
  • Halobatasol Proionate
  • Halobetasol Propionate (200 mg)
  • Miracorten
  • HalobetasolPropionate&gt
  • 21-Chloro-6alpha,9alpha-difluoro-11beta,17alpha-dihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
  • Halobetasol propionate ISO 9001：2015 REACH
  • Halobetasol Propionate D5Q: What is Halobetasol Propionate D5 Q: What is the CAS Number of Halobetasol Propionate D5
  • Halobetasol PropionateQ: What is Halobetasol Propionate Q: What is the CAS Number of Halobetasol Propionate Q: What is the storage condition of Halobetasol Propionate Q: What are the applications of Halobetasol Propionate
  • Halobetasol Propionate (1302906)
  • (6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
  • 21-chloro-6alpha,9-difChemicalbookluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione17-propionate
  • 66852-54-8
  • C25H31ClF2O5
  • Inhibitors
  • Steroids