ChemicalBook > CAS DataBase List > Halobetasol propionate

Halobetasol propionate

Product Name
Halobetasol propionate
CAS No.
66852-54-8
Chemical Name
Halobetasol propionate
Synonyms
CGP-14458;BMY-30056;Ultravate;Miracorten;ulobetasol propionate;Uiobetasol Propionate;Halobatasol Proionate;HALOBETASOL PROPIONATE;HalobetasolPropionate>Halobetasol Propionate (200 mg)
CBNumber
CB4305095
Molecular Formula
C25H31ClF2O5
Formula Weight
484.96
MOL File
66852-54-8.mol
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Halobetasol propionate Property

Melting point:
213-215°C
Boiling point:
570.7±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.55±0.70(Predicted)
color 
White to Off-White
InChIKey
BDSYKGHYMJNPAB-QNGYMBKVNA-N
SMILES
O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|
CAS DataBase Reference
66852-54-8(CAS DataBase Reference)
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Safety

HS Code 
2937220000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1302906
Product name
Halobetasol propionate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200MG
Price
$174.4
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
10mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
23781
Product name
Halobetasol Propionate
Purity
≥95%
Packaging
50mg
Price
$169
Updated
2024/03/01
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Halobetasol propionate Chemical Properties,Usage,Production

Description

Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis.  It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis.

Chemical Properties

White Solid

Originator

Ciba-Geigy (Switzerland)

Uses

Halobetasol propionate is a corticosteroid (cortisone-like medicine or steroid). As an anti-inflammatory drug, halobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis.This medicine is available only with doctor's prescription.

Definition

ChEBI: Ulobetasol propionate is a corticosteroid hormone.

brand name

Ultravate (Westwood-Squibb).

Halobetasol propionate Preparation Products And Raw materials

Raw materials

Acetylacetone Methanesulfonyl chloride Lithium chloride

Preparation Products

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View Lastest Price from Halobetasol propionate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500
Release date
2023-07-31
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-01
Hebei Mojin Biotechnology Co., Ltd
Product
Halobetasol propionate 66852-54-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-05-19

66852-54-8, Halobetasol propionateRelated Search:

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  • 66852-54-8
  • C25H31ClF2O5
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