Biotin-PEG2-Acid

Product Name: Biotin-PEG2-Acid
CAS No.: 1365655-89-5
Chemical Name: Biotin-PEG2-Acid
Synonyms: Biotin-PEG2-Acid;Biotin-PEG2-COOH;Biotin PEG2-C2-COOH;(+)-Biotin-PEG2-acid;(+)-Biotin-PEG2-CH2CH2COOH;3-(2-(2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-[[5-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]-, rel-
CBNumber: CB43062388
Molecular Formula: C17H29N3O6S
Formula Weight: 403.49
MOL File: 1365655-89-5.mol

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Biotin-PEG2-Acid Property

Boiling point:: 752.2±60.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: -20°C, protect from light, stored under argon
solubility: Soluble in DMSO, DMF
pka: 4.28±0.10(Predicted)
form: solid
color: White
InChIKey: SDOAIZRTYJIBBG-RMBTXETHNA-N
SMILES: C(O)(=O)CCOCCOCCNC(=O)CCCC[C@@H]1[C@]2([H])NC(=O)N[C@]2([H])CS1 |&1:18,19,25,r|

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Safety

HS Code: 2918999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-20613
Product name: Biotin-PEG2-acid
Purity: 98%
Packaging: 100mg
Price: $150
Updated: 2021/12/16

BroadPharm

Product number: BP-20613
Product name: Biotin-PEG2-acid
Purity: 98%
Packaging: 500mg
Price: $390
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: POL0002383
Product name: BIOTIN-PEG2-ACID
Purity: 95.00%
Packaging: 5MG
Price: $499.66
Updated: 2021/12/16

BroadPharm

Product number: BP-20613
Product name: Biotin-PEG2-acid
Purity: 98%
Packaging: 1g
Price: $545
Updated: 2021/12/16

purepeg

Product number: 246802
Product name: (+)-Biotin-PEG2-CH2CH2COOH
Purity: min.97%
Packaging: 250mg
Price: $180
Updated: 2021/12/16

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Biotin-PEG2-Acid Chemical Properties,Usage,Production

Description

Biotin-PEG2-acid is reactive with amine-containing macromolecule. The hydrophilic PEG arm improves water solubility. The biotin groups serve as an affinity label towards the proteins avidin and streptavidin.

Uses

Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs; Non-cleavable Linker

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Biotin-PEG2-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-PEG2-Acid Suppliers

China 70 United Kingdom 1 United States 7 Global 78

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

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View Lastest Price from Biotin-PEG2-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG2-COOH 1365655-89-5
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-30

1365655-89-5, Biotin-PEG2-AcidRelated Search:

Biotin-PEG5-CH2CH2COOH Biotin-PEG8-acid 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Biotin-PEG4-N3 Biotin-PEG6-Mal Biotin-PEG3-Mal 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine [3aS,4S,6aR,(+)]-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid 5-oxide Biotin-PEG3-N3 9-biotinlaMino-4,7-dioxanonanoic acid N-hydroxysucciniMidyl ester 21-[D(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid Biotin-PEG7-Azide Biotin-PEG5-azide 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG3-propionic acid N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Biotin-PEG12-Acid

Biotin-PEG2-Acid

(+)-Biotin-PEG2-CH2CH2COOH

Biotin-PEG2-COOH

Propanoic acid, 3-[2-[2-[[5-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]-, rel-

(+)-Biotin-PEG2-acid

Biotin PEG2-C2-COOH

3-(2-(2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)propanoic acid

1365655-89-5

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