ChemicalBook > CAS DataBase List > m-PEG4-t-butyl ester
m-PEG4-t-butyl ester
- Product Name
- m-PEG4-t-butyl ester
- CAS No.
- 883554-11-8
- Chemical Name
- m-PEG4-t-butyl ester
- Synonyms
- m-PEG4-Boc;m-PEG4-COOtBu;mPEG3-CH2CH2COOtBu;mPEG4-CH2CH2COOtBu;m-PEG4-t-butyl ester;tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate;4,7,10,13-Tetraoxatetradecanoic acid, 1,1-dimethylethyl ester;tert-Butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate/m-PEG4-t-butyl ester
- CBNumber
- CB43062575
- Molecular Formula
- C14H28O6
- Formula Weight
- 292.37
- MOL File
- 883554-11-8.mol
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m-PEG4-t-butyl ester Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to off-white
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22413
- Product name
- m-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $380
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22413
- Product name
- m-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $580
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1642
- Product name
- m-PEG4-t-butyl ester
- Packaging
- 500mg
- Price
- $740
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22413
- Product name
- m-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 5G
- Price
- $1400
- Updated
- 2021/12/16
Absolute Chiral
- Product number
- P1015-00-N
- Product name
- tert-butyl2,5,8,11-tetraoxatetradecan-14-oate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $228
- Updated
- 2021/12/16
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m-PEG4-t-butyl ester Chemical Properties,Usage,Production
Description
m-PEG4-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
IC 50
PEGs; Cleavable Linker
References
[1] Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.
[2] Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.
m-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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m-PEG4-t-butyl ester Suppliers
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View Lastest Price from m-PEG4-t-butyl ester manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- m-PEG4-Boc 883554-11-8
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
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