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m-PEG4-t-butyl ester

Product Name
m-PEG4-t-butyl ester
CAS No.
883554-11-8
Chemical Name
m-PEG4-t-butyl ester
Synonyms
m-PEG4-Boc;m-PEG4-COOtBu;mPEG3-CH2CH2COOtBu;mPEG4-CH2CH2COOtBu;m-PEG4-t-butyl ester;tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate;4,7,10,13-Tetraoxatetradecanoic acid, 1,1-dimethylethyl ester;tert-Butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate/m-PEG4-t-butyl ester
CBNumber
CB43062575
Molecular Formula
C14H28O6
Formula Weight
292.37
MOL File
883554-11-8.mol
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m-PEG4-t-butyl ester Property

storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22413
Product name
m-PEG4-t-butylester
Purity
98%
Packaging
500mg
Price
$380
Updated
2021/12/16
BroadPharm
Product number
BP-22413
Product name
m-PEG4-t-butylester
Purity
98%
Packaging
1g
Price
$580
Updated
2021/12/16
Apolloscientific
Product number
BIPG1642
Product name
m-PEG4-t-butyl ester
Packaging
500mg
Price
$740
Updated
2021/12/16
BroadPharm
Product number
BP-22413
Product name
m-PEG4-t-butylester
Purity
98%
Packaging
5G
Price
$1400
Updated
2021/12/16
Absolute Chiral
Product number
P1015-00-N
Product name
tert-butyl2,5,8,11-tetraoxatetradecan-14-oate
Purity
95%
Packaging
250mg
Price
$228
Updated
2021/12/16
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m-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

m-PEG4-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC 50

PEGs; Cleavable Linker

References

[1] Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.
[2] Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.

m-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG4-t-butyl ester Suppliers

Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
354
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-(0)57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Shanghai Chenghe Medical Technology Co. Ltd.
Tel
021-021-54382182 18601603956
Email
18601603956@163.com
Country
China
ProdList
1255
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
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View Lastest Price from m-PEG4-t-butyl ester manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
m-PEG4-Boc 883554-11-8
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19