m-PEG4-t-butyl ester

Product Name: m-PEG4-t-butyl ester
CAS No.: 883554-11-8
Chemical Name: m-PEG4-t-butyl ester
Synonyms: m-PEG4-Boc;m-PEG4-COOtBu;mPEG3-CH2CH2COOtBu;mPEG4-CH2CH2COOtBu;m-PEG4-t-butyl ester;tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate;4,7,10,13-Tetraoxatetradecanoic acid, 1,1-dimethylethyl ester;tert-Butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate/m-PEG4-t-butyl ester
CBNumber: CB43062575
Molecular Formula: C14H28O6
Formula Weight: 292.37
MOL File: 883554-11-8.mol

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m-PEG4-t-butyl ester Property

storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22413
Product name: m-PEG4-t-butylester
Purity: 98%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-22413
Product name: m-PEG4-t-butylester
Purity: 98%
Packaging: 1g
Price: $580
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1642
Product name: m-PEG4-t-butyl ester
Packaging: 500mg
Price: $740
Updated: 2021/12/16

BroadPharm

Product number: BP-22413
Product name: m-PEG4-t-butylester
Purity: 98%
Packaging: 5G
Price: $1400
Updated: 2021/12/16

Absolute Chiral

Product number: P1015-00-N
Product name: tert-butyl2,5,8,11-tetraoxatetradecan-14-oate
Purity: 95%
Packaging: 250mg
Price: $228
Updated: 2021/12/16

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m-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

m-PEG4-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC 50

PEGs; Cleavable Linker

References

[1] Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.
[2] Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.

m-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG4-t-butyl ester Suppliers

China 38 India 1 United Kingdom 1 United States 5 Global 45

Nanjing Junnahe Biopharmaceutical Co., Ltd

Tel: 025-58367986 17351780683
Fax: QQ3209878052
Email: amy.xiang@ally-chem.com
Country: China
ProdList: 354
Advantage: 60

ShangHai D&B Biological Science and Technology Co.Ltd

Tel: 400-008-9730,021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
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Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
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Jinan elephant international trading co., LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
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Email: psaitong@jm-bio.com
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Capot Chemical Co.,Ltd.

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Fax: +86-571-85864795
Email: sales@capot.com
Country: China
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Xi'an Confluore Biological Technology Co., Ltd.

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Email: 1924344760@qq.com
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Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
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Shanghai Chenghe Medical Technology Co. Ltd.

Tel: 021-021-54382182 18601603956
Email: 18601603956@163.com
Country: China
ProdList: 1275
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32469
Advantage: 58

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View Lastest Price from m-PEG4-t-butyl ester manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: m-PEG4-Boc 883554-11-8
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

883554-11-8, m-PEG4-t-butyl esterRelated Search:

2,5,8,11,14-pentaoxahexadecan-16-oic acid Amino-PEG11-Amine O,O′-Bis(2-aMinoethyl)polyethylene Glycol Amino-PEG9-Amine [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 3,6,9,12,15,21,24,27,30-Decaoxadotriacontane-1,32-diaMine 1,14-diamino-3,6,9,12-tetraoxatetradecane 3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontanoic acid mPEG15-acetic acid 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AMINE mPEG6-CH2COOH 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diamine 3,6,9-trioxaundecamethylenediamine 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid 3,6,9,1,15,18,21,24-Octaoxahexacosane-1-26-diaMi tert-Butyl acetate Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)

m-PEG4-t-butyl ester

mPEG4-CH2CH2COOtBu

tert-Butyl 3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propionate/m-PEG4-t-butyl ester

m-PEG4-Boc

4,7,10,13-Tetraoxatetradecanoic acid, 1,1-dimethylethyl ester

mPEG3-CH2CH2COOtBu

tert-butyl 2,5,8,11-tetraoxatetradecan-14-oate

m-PEG4-COOtBu

883554-11-8