ChemicalBook > CAS DataBase List > TM5007
TM5007
- Product Name
- TM5007
- CAS No.
- 342595-05-5
- Chemical Name
- TM5007
- Synonyms
- TM5007;TM 5007,inhibit,TM5007,PAI-1,Plasminogen activator inhibitor-1,Inhibitor,TM-5007;[2,3'-Bithiophene]-4'-carboxylic acid, 5',5'''-[(1,6-dioxo-1,6-hexanediyl)diimino]bis-;5'-[5-({4'-carboxy-[2,3'-bithiophen]-5'-yl}carbamoyl)pentanamido]-[2,3'-bithiophene]-4'-carboxylic acid
- CBNumber
- CB43067585
- Molecular Formula
- C24H20N2O6S4
- Formula Weight
- 560.69
- MOL File
- 342595-05-5.mol
More
Less
TM5007 Property
- Boiling point:
- 781.7±60.0 °C(Predicted)
- Density
- 1.544±0.06 g/cm3(Predicted)
- pka
- 3.93±0.40(Predicted)
More
Less
N-Bromosuccinimide Price
AK Scientific
- Product number
- SYN5237
- Product name
- TM5007
- Packaging
- 10mg
- Price
- $320
- Updated
- 2021/12/16
More
Less
TM5007 Chemical Properties,Usage,Production
Uses
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].
References
[1] Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7. DOI:10.1161/ATVBAHA.107.157479
TM5007 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
TM5007 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58