Sofosbuvir Impurity23

Product Name: Sofosbuvir Impurity23
Chemical Name: Sofosbuvir Impurity23
Synonyms: Sofosbuvir Impurity23;α-Sofosbuvir Desphosphate;((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate;(2R,3S,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
CBNumber: CB43118061
Formula Weight: 0
MOL File: Mol file

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S675620
Product name: α-SofosbuvirDesphosphate
Packaging: 10mg
Price: $1540
Updated: 2021/12/16

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Sofosbuvir Impurity23 Chemical Properties,Usage,Production

Uses

α-Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.

Sofosbuvir Impurity23 Preparation Products And Raw materials

Raw materials

Preparation Products

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Sofosbuvir Impurity23

α-Sofosbuvir Desphosphate

(2R,3S,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate