BAFILOMYCIN B1
- Product Name
- BAFILOMYCIN B1
- CAS No.
- 88899-56-3
- Chemical Name
- BAFILOMYCIN B1
- Synonyms
- CID 74030053;BAFILOMYCIN B1;BAFILOMYCIN B1 USP/EP/BP;ino)carbonyl)-2-methoxy-24-methyl-;bafilomycin b1from streptomyces sp.;BafilomycinB1fromStreptomycesgriseus;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
- CBNumber
- CB4312754
- Molecular Formula
- C44H65NO13
- Formula Weight
- 815.99
- MOL File
- 88899-56-3.mol
BAFILOMYCIN B1 Property
- storage temp.
- −20°C
- solubility
- DMSO: Soluble; Methanol: Unstable
- form
- powder or crystals
- color
- faint yellow to yellow
- BRN
- 4640118
- Stability:
- Hygroscopic
Safety
- Hazard Codes
- T+
- Risk Statements
- 26/27/28
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 3462 6.1/PG 1
- WGK Germany
- 3
- RTECS
- NG8841000
- F
- 10-21
- HazardClass
- 3
- HS Code
- 2941900000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 11707
- Product name
- Bafilomycin B1 from Streptomyces sp.
- Purity
- ≥80% (HPLC)
- Packaging
- 1mg
- Price
- $218
- Updated
- 2022/05/15
- Product number
- J67463
- Product name
- Bafilomycin B1, 0.1 mg/ml in methanol, sterile-filtered
- Packaging
- 1ml
- Price
- $321
- Updated
- 2023/06/20
- Product number
- 14005
- Product name
- Bafilomycin B1
- Purity
- ≥97%
- Packaging
- 100μg
- Price
- $41
- Updated
- 2024/03/01
- Product number
- 14005
- Product name
- Bafilomycin B1
- Purity
- ≥97%
- Packaging
- 1mg
- Price
- $142
- Updated
- 2024/03/01
- Product number
- 14005
- Product name
- Bafilomycin B1
- Purity
- ≥97%
- Packaging
- 5mg
- Price
- $505
- Updated
- 2024/03/01
BAFILOMYCIN B1 Chemical Properties,Usage,Production
Description
Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.
Uses
Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.
BAFILOMYCIN B1 Preparation Products And Raw materials
Raw materials
Preparation Products
BAFILOMYCIN B1 Suppliers
- Tel
- --
- Fax
- --
- Country
- Germany
- ProdList
- 4426
- Advantage
- 68
- Tel
- --
- Fax
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- Country
- Germany
- ProdList
- 1136
- Advantage
- 62
View Lastest Price from BAFILOMYCIN B1 manufacturers
- Product
- BAFILOMYCIN B1 88899-56-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19