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BAFILOMYCIN B1

Product Name
BAFILOMYCIN B1
CAS No.
88899-56-3
Chemical Name
BAFILOMYCIN B1
Synonyms
CID 74030053;BAFILOMYCIN B1;BAFILOMYCIN B1 USP/EP/BP;ino)carbonyl)-2-methoxy-24-methyl-;bafilomycin b1from streptomyces sp.;BafilomycinB1fromStreptomycesgriseus;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
CBNumber
CB4312754
Molecular Formula
C44H65NO13
Formula Weight
815.99
MOL File
88899-56-3.mol
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BAFILOMYCIN B1 Property

storage temp. 
−20°C
solubility 
DMSO: Soluble; Methanol: Unstable
form 
powder or crystals
color 
faint yellow to yellow
BRN 
4640118
Stability:
Hygroscopic
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
36/37/39-45
RIDADR 
UN 3462 6.1/PG 1
WGK Germany 
3
RTECS 
NG8841000
F 
10-21
HazardClass 
3
HS Code 
2941900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
11707
Product name
Bafilomycin B1 from Streptomyces sp.
Purity
≥80% (HPLC)
Packaging
1mg
Price
$218
Updated
2022/05/15
Alfa Aesar
Product number
J67463
Product name
Bafilomycin B1, 0.1 mg/ml in methanol, sterile-filtered
Packaging
1ml
Price
$321
Updated
2023/06/20
Cayman Chemical
Product number
14005
Product name
Bafilomycin B1
Purity
≥97%
Packaging
100μg
Price
$41
Updated
2024/03/01
Cayman Chemical
Product number
14005
Product name
Bafilomycin B1
Purity
≥97%
Packaging
1mg
Price
$142
Updated
2024/03/01
Cayman Chemical
Product number
14005
Product name
Bafilomycin B1
Purity
≥97%
Packaging
5mg
Price
$505
Updated
2024/03/01
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BAFILOMYCIN B1 Chemical Properties,Usage,Production

Description

Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.

Uses

Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.

BAFILOMYCIN B1 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAFILOMYCIN B1 Suppliers

China 42 Germany 2 India 1 Switzerland 2 United Kingdom 7 United States 13 Global 67
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74
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View Lastest Price from BAFILOMYCIN B1 manufacturers

Dideu Industries Group Limited
Product
BAFILOMYCIN B1 88899-56-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-19

88899-56-3, BAFILOMYCIN B1Related Search:

B-1 Doxycycline BAFILOMYCIN B2 BAFILOMYCIN A1 (DRY ICE) Bafilomycin A2 Bafilomycin C2 Bafilomycin A1 from Streptomycesgriseus, 10 ug,BAFILOMYCIN A1, 98+%,BAFILOMYCIN A1 95%,BAFILOMYCIN A1, STREPTOMYCES GRISEUS,BAFILOMYCIN A1 Bafilomycin D2' Bafilomycin E Bafilomycin D1 BAFILOMYCIN C1 bafilomycin D BAFILOMYCIN B1 MONOHYDRATE BAFILOMYCIN B2 FROM STREPTOMYCES GRISEUS

  • BAFILOMYCIN B1
  • BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES
  • BafilomycinB1fromStreptomycesgriseus
  • bafilomycin b1from streptomyces sp.
  • hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am
  • ino)carbonyl)-2-methoxy-24-methyl-
  • 37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin
  • 2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
  • BAFILOMYCIN B1 USP/EP/BP
  • CID 74030053
  • 88899-56-3
  • C44H65NO13
  • Antibiotics
  • Antibiotics A-F
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  • BioChemical
  • Antibiotic
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  • Antibacterial
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  • Antibiotics A-FAntibiotics
  • Antibiotics by Application
  • AntifungalAntibiotics
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Chemical Structure Class
  • Inhibits an EnzymeAntibiotics
  • Mechanism of Action
  • Spectrum of Activity