Propargyl-PEG5-CH2CO2H
- Product Name
- Propargyl-PEG5-CH2CO2H
- CAS No.
- 1429934-37-1
- Chemical Name
- Propargyl-PEG5-CH2CO2H
- Synonyms
- Propargyl-PEG5;Propargyl-PEG5-CH2COOH;Propargyl-PEG5-CH2CO2H;Propargyl-PEG4-acetic Acid;3,6,9,12,15-pentaoxaoctadec-17-ynoic acid;Propargyl-PEG4-CH2COOH/3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid
- CBNumber
- CB43163117
- Molecular Formula
- C13H22O7
- Formula Weight
- 290.31
- MOL File
- 1429934-37-1.mol
Propargyl-PEG5-CH2CO2H Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23125
- Product name
- Propargyl-PEG5-CH2CO2H
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- AS104182
- Product name
- Propargyl-PEG4-CH2COOH
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $294
- Updated
- 2021/12/16
- Product number
- BP-23125
- Product name
- Propargyl-PEG5-CH2CO2H
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- AS104182
- Product name
- Propargyl-PEG4-CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $588
- Updated
- 2021/12/16
- Product number
- BP-23125
- Product name
- Propargyl-PEG5-CH2CO2H
- Purity
- 98%
- Packaging
- 500mg
- Price
- $780
- Updated
- 2021/12/16
Propargyl-PEG5-CH2CO2H Chemical Properties,Usage,Production
Description
Propargyl-PEG5-CH2CO2H is an alkyne linker with a carboxylic acid. The carboxylic acid can react with primary amines to form stable amide bonds; activator (e.g. EDC, or HATU) is needed. The alkyne group can participate in copper catalyzed azide-alkyne Click Chemistry to form stable triazole linkage.
Uses
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG5-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG5-CH2CO2H Suppliers
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