2'-Deoxy-L-thymidine

Product Name: 2'-Deoxy-L-thymidine
CAS No.: 3424-98-4
Chemical Name: 2'-Deoxy-L-thymidine
Synonyms: Ldt;L-Dt;Sebivo;NV 02B;Epavudine;Aids112549;elbivudine;Aids-112549;BETA-L-THYMIDINE;L-Deoxythymidine
CBNumber: CB4321891
Molecular Formula: C10H14N2O5
Formula Weight: 242.23
MOL File: 3424-98-4.mol

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2'-Deoxy-L-thymidine Property

Melting point:: 188-190°C
alpha: D20 -20.3° (c = 0.192 in water)
Density: 1.452±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: H2O: soluble10mg/mL (clear solution)
form: powder
pka: 9.55±0.10(Predicted)
color: white to beige
optical activity: [α]/D -15 to -22°, c = 1 in H2O
InChIKey: IQFYYKKMVGJFEH-CSMHCCOUSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
RTECS: UV9048500
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0293
Product name: Telbivudine
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $130
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0293
Product name: Telbivudine
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $523
Updated: 2024/03/01

Cayman Chemical

Product number: 21453
Product name: Telbivudine
Packaging: 10mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 21453
Product name: Telbivudine
Packaging: 100mg
Price: $656
Updated: 2024/03/01

Cayman Chemical

Product number: 21453
Product name: Telbivudine
Packaging: 5mg
Price: $57
Updated: 2024/03/01

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2'-Deoxy-L-thymidine Chemical Properties,Usage,Production

Description

Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.

Chemical Properties

2'-Deoxy-L-thymidine is White Solid

Originator

Idenix (US)

Uses

Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.

Uses

Telbivudine(Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection. Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.

brand name

(Novirio).

2'-Deoxy-L-thymidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Deoxy-L-thymidine Suppliers

Brazil 1 Canada 2 China 241 Denmark 1 Germany 3 India 11 Poland 1 The Netherlands 1 United Kingdom 9 United States 36 Global 306

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 991
Advantage: 55

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
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Advantage: 56

Wuhu Huaren Science and Technology Co., Ltd.

Tel: 0553-0553-5842013-801 18155347026
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Country: China
ProdList: 296
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Adamas Reagent, Ltd.

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Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
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Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

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View Lastest Price from 2'-Deoxy-L-thymidine manufacturers

Hebei Duling International Trade Co. LTD

Product: 2'-Deoxy-L-thymidine 3424-98-4
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-04-20

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Telbivudine 3424-98-4
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 99.5%min
Supply Ability: 10kg
Release date: 2021-08-20

Hebei Mojin Biotechnology Co., Ltd

Product: 2'-Deoxy-L-thymidine 3424-98-4
Price: US $20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000kg
Release date: 2023-08-17

3424-98-4, 2'-Deoxy-L-thymidineRelated Search:

CHLOROPHOSPHONAZO III Thymidine 3'-Azido-3'-deoxy-D-thymidine Clevudine DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* 3'-Deoxy-D-thymidine 3'-AMINO-3'-DEOXY-D-THYMIDINE 2',3'-Didehydro-3'-deoxy-D-thymidine 5'-AZIDO-5'-DEOXY-D-THYMIDINE 3'-Azido-3'-deoxy-D-thymidine5'-monophosphatesodiumsalt 2'-Deoxy-L-thymidine-d3 5-METHYL-1-(β-L-RIBOFURANOSYL)URACIL 3'-Azido-3'-deoxy-D-thymidine-b-D-glucuronidesodiumsalt 3'-Iodo-3'-deoxy-D-thymidine 5'-Amino-5'-deoxy-D-thymidine 2'-Deoxy-L-thymidine Deoxynucleotide Deoxidizer

BETA-L-THYMIDINE

2'-DEOXY-L-THYMIDINE

L-Thymidine(Telbivudine)

1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione

Β-L-2'-DEOXY-THYMIDINE

2'-Deoxy-L-thyMidine(Telbivudine)

Telbivudine(Tyzeka, Sebivo)

1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-Methyl-

Telbivudine(L-ThyMidine,LDT-600)

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione

2,4(1H,3H)-PyriMidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-Methyl-

Sebivo

Telbivudine(L-ThyMidine)

Telbivudine, >=98%

1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

1-(2-deoxy--L-erythro-pentofuranosyl)thymine

Epavudine

NV 02B

Aids112549

Aids-112549

L-Deoxythymidine

Ldt

L-Dt

Thymine, 1-(2-deoxy-.beta.-L-erythro-pentofuranosyl)-

1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione

2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methyl-

elbivudine

2'-Deoxy-L-thymidine USP/EP/BP

Telbivudine (Epavudine)

Telbivudine 13C 15N2

Inhibitor,Telbivudine,inhibit,HBV,Hepatitis B virus

1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

2'-Deoxy-L-thymidine

3424-98-4

Anti-virals

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Carbohydrates & Derivatives

Intermediates & Fine Chemicals

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Pharmaceuticals

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Amines

API

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Heterocycles