2'-Deoxy-L-thymidine
- Product Name
- 2'-Deoxy-L-thymidine
- CAS No.
- 3424-98-4
- Chemical Name
- 2'-Deoxy-L-thymidine
- Synonyms
- Ldt;L-Dt;Sebivo;NV 02B;Epavudine;Aids112549;elbivudine;Aids-112549;BETA-L-THYMIDINE;L-Deoxythymidine
- CBNumber
- CB4321891
- Molecular Formula
- C10H14N2O5
- Formula Weight
- 242.23
- MOL File
- 3424-98-4.mol
2'-Deoxy-L-thymidine Property
- Melting point:
- 188-190°C
- alpha
- D20 -20.3° (c = 0.192 in water)
- Density
- 1.452±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: soluble10mg/mL (clear solution)
- form
- powder
- pka
- 9.55±0.10(Predicted)
- color
- white to beige
- optical activity
- [α]/D -15 to -22°, c = 1 in H2O
- InChIKey
- IQFYYKKMVGJFEH-CSMHCCOUSA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0293
- Product name
- Telbivudine
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- SML0293
- Product name
- Telbivudine
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $523
- Updated
- 2024/03/01
- Product number
- 21453
- Product name
- Telbivudine
- Packaging
- 10mg
- Price
- $100
- Updated
- 2024/03/01
- Product number
- 21453
- Product name
- Telbivudine
- Packaging
- 100mg
- Price
- $656
- Updated
- 2024/03/01
- Product number
- 21453
- Product name
- Telbivudine
- Packaging
- 5mg
- Price
- $57
- Updated
- 2024/03/01
2'-Deoxy-L-thymidine Chemical Properties,Usage,Production
Description
Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.
Chemical Properties
2'-Deoxy-L-thymidine is White Solid
Originator
Idenix (US)
Uses
Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.
Uses
Telbivudine(Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection. Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic
Definition
ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.
brand name
(Novirio).
2'-Deoxy-L-thymidine Preparation Products And Raw materials
Raw materials
Preparation Products
2'-Deoxy-L-thymidine Suppliers
View Lastest Price from 2'-Deoxy-L-thymidine manufacturers
- Product
- 2'-Deoxy-L-thymidine 3424-98-4
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-04-20
- Product
- Telbivudine 3424-98-4
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99.5%min
- Supply Ability
- 10kg
- Release date
- 2021-08-20
- Product
- 2'-Deoxy-L-thymidine 3424-98-4
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000kg
- Release date
- 2023-08-17