NIGERICIN SODIUM SALT

Product Name: NIGERICIN SODIUM SALT
CAS No.: 28380-24-7
Chemical Name: NIGERICIN SODIUM SALT
Synonyms: x-464;Helix c;HELIXIN C;NIGERICIN;Aids003767;Aids-003767;AZALOMYCIN M;NIGERICIN NA;POLYETHERIN A;Antibiotic M 2
CBNumber: CB4331016
Molecular Formula: C40H68O11
Formula Weight: 724.96
MOL File: 28380-24-7.mol

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NIGERICIN SODIUM SALT Property

Melting point:: 183.5-185°
alpha: D24 +36.2° (c = 0.842 in CHCl3)
Boiling point:: 779.9±60.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: chloroform: 10 mg/mL, clear, colorless
pka: 4.39±0.10(Predicted)

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Safety

Hazard Codes: T,Xi
Risk Statements: 25-36/37/38
Safety Statements: 26-36/37/39-45-36
RIDADR: UN 3462 6.1/PG 3
WGK Germany: 3
RTECS: QT6840000
F: 10
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29419090
Toxicity: LD50 in mice (mg/kg): 10-15 i.p. (Shoji); also reported as 2.5 i.p. (Harned)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0003572
Product name: NIGERICIN
Purity: 95.00%
Packaging: 5MG
Price: $673.61
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003572
Product name: NIGERICIN
Purity: 95.00%
Packaging: 10MG
Price: $686.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003572
Product name: NIGERICIN
Purity: 95.00%
Packaging: 25MG
Price: $737.58
Updated: 2021/12/16

AvaChem

Product number: 2066
Product name: Nigericin
Packaging: 1g
Price: $3250
Updated: 2021/12/16

AvaChem

Product number: 2066
Product name: Nigericin
Packaging: 5mg
Price: $45
Updated: 2021/12/16

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NIGERICIN SODIUM SALT Chemical Properties,Usage,Production

Uses

Nigericin is a polyether antibiotic produced by Streptomyces, notably S. hygroscopicus, isolated in the 1950s. Its complex structure was finally elucidated in 1968. Nigericin is an ionophore, possessing very high affinity for monovalent cations such as Na+ and K+. Nigericin disrupts membrane potential and Golgi apparatus in mitochondria. Although nigericin can be isolated as the free acid (under acidic conditions), like most ionophores it is extracted into organic solvents and is most conveniently isolated as a salt. In vitro, nigericin has broad biological activity against Gram positive bacteria, fungi, tumour cell lines and some viruses, including HIV. Nigericin is the most common member of the polyether class which are common false positives in in vitro screening bioassays using crude microbial extracts. They are thus important standards for dereplication.

Definition

ChEBI: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus.

NIGERICIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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NIGERICIN SODIUM SALT Suppliers

China 90 Europe 1 Germany 4 India 1 Japan 1 Switzerland 2 United Kingdom 6 United States 18 Global 123

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View Lastest Price from NIGERICIN SODIUM SALT manufacturers

Career Henan Chemical Co

Product: NIGERICIN SODIUM SALT 28380-24-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%-99.9%
Supply Ability: 200kg
Release date: 2020-01-12

28380-24-7, NIGERICIN SODIUM SALTRelated Search:

1,16-HEXADECANEDIOL n-Octacosane NIGERICIN SODIUM SALT TRICOSANOIC ACID CAPRIC ACID SODIUM SALT N-NONACOSANE 1-TERT-BUTOXY-2-PROPANOL 3,6,9,12-tetraoxahexadecan-1-ol 11-HENEICOSANOL (R)-1,2-DODECANEDIOL 1-HEXACOSANOL 2-(OCTADECYLOXY)ETHANOL N-CAPROIC ACID SODIUM SALT TRI(PROPYLENE GLYCOL) PROPYL ETHER Dipropylene Glycol Dimethyl Ether Sodium stearate Nigericin sodium salt 1,3,3-TRIMETHOXYBUTANE

(2R)-2-((3S)-6-{[2-((5S)-5-{(3S)-5-[(3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethylperhydro-2H-pyran-2-yl]-3-methyloxolan-2-yl}-5-methyloxolan-2-yl)(2S,4R,9R,10R)-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methylperhydro-2H-pyran-2-yl)propanoic acid

28643-80-3 (Sodium salt)

Aids003767

Aids-003767

Helix c

AZALOMYCIN M

HELIXIN C

ANTIBIOTIC K178

ANTIBIOTIC K178 SODIUM SALT

ANTIBIOTIC X-464

Polyetherin A, AzaloMycin M, Helixin C, K 178, X 464

Antibiotic M 2

x-464

NIGERICIN

NIGERICIN NA

NIGERICIN, NA SALT

NIGERICIN, SODIUM SALT, STREPTOMYCES HYGROSCOPICUS

POLYETHERIN A

Nigericin from Streptomyces hygroscopicus

Antibiotic K178 sodium salt, Azalomycin M

nigericin sodium

nigericin sodium from streptomyces*hygroscopicus

nigericin sodium salt from streptomyces hygroscopicus

NIGERICIN APPOX. 95%

28380-24-7

C40H68O11

BioChemical

Antibiotics A to Z

Antibiotics N-S

Antibiotics

antibiotic