ChemicalBook > CAS DataBase List > Hydroxy-PEG5-methyl ester
Hydroxy-PEG5-methyl ester
- Product Name
- Hydroxy-PEG5-methyl ester
- CAS No.
- 2100306-80-5
- Chemical Name
- Hydroxy-PEG5-methyl ester
- Synonyms
- HO-PEG5-COOMe;CAS_2100306-80-5;HO-PEG5-CH2CH2COOMe;Hydroxy-PEG5-methyl ester;Hydroxy-PEG5-C2-methyl ester;methyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-hydroxy-, methyl ester
- CBNumber
- CB43369490
- Molecular Formula
- C14H28O8
- Formula Weight
- 324.37
- MOL File
- 2100306-80-5.mol
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Hydroxy-PEG5-methyl ester Property
- Boiling point:
- 414.8±40.0 °C(Predicted)
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23624
- Product name
- Hydroxy-PEG5-methylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
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Hydroxy-PEG5-methyl ester Chemical Properties,Usage,Production
Description
Hydroxy-PEG5-methyl ester is a PEG linker containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition.
Uses
Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Hydroxy-PEG5-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Hydroxy-PEG5-methyl ester Suppliers
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View Lastest Price from Hydroxy-PEG5-methyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- HO-PEG5-COOMe 2100306-80-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25