Hydroxy-PEG5-methyl ester
- Product Name
- Hydroxy-PEG5-methyl ester
- CAS No.
- 2100306-80-5
- Chemical Name
- Hydroxy-PEG5-methyl ester
- Synonyms
- HO-PEG5-COOMe;CAS_2100306-80-5;HO-PEG5-CH2CH2COOMe;Hydroxy-PEG5-methyl ester;Hydroxy-PEG5-C2-methyl ester;methyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-hydroxy-, methyl ester
- CBNumber
- CB43369490
- Molecular Formula
- C14H28O8
- Formula Weight
- 324.37
- MOL File
- 2100306-80-5.mol
Hydroxy-PEG5-methyl ester Property
- Boiling point:
- 414.8±40.0 °C(Predicted)
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23624
- Product name
- Hydroxy-PEG5-methylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
Hydroxy-PEG5-methyl ester Chemical Properties,Usage,Production
Description
Hydroxy-PEG5-methyl ester is a PEG linker containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition.
Uses
Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Hydroxy-PEG5-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hydroxy-PEG5-methyl ester manufacturers
- Product
- HO-PEG5-COOMe 2100306-80-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25