(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL

Uses

Product Name: (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL
CAS No.: 133082-13-0
Chemical Name: (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL
Synonyms: (1S)-1-(2-ChL;(S)-1-(2-chlorophenyl)ethane-1,2-diol;(S)-2-(2-CHLOROPHENYL)ETHANE-1,2-DIOL;(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL;(1S)-1-(2-Chlorophenyl)-1,2-ethanediol;(1S)-1-(2-Chlorophenyl)ethane-1,2-diol l;(S)-(+)-1-(2-CHLOROPHENYL)-1 2- &;(S)-(+)-1-(2-CHLOROPHENYL)-1,2-ETHANEDIOL;1,2-Ethanediol, 1-(2-chlorophenyl)-, (1S)-;(1S)-1-(2-Chlorophenyl)ethane-1,2-diol,95%
CBNumber: CB4341367
Molecular Formula: C8H9ClO2
Formula Weight: 172.61
MOL File: 133082-13-0.mol

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(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL Property

Melting point:: 68-75 °C(lit.)
Boiling point:: 293 °C(lit.)
Density: 1.1910 (rough estimate)
refractive index: 1.5530 (estimate)
Flash point:: 108 °C
storage temp.: Sealed in dry,Room Temperature
pka: 13.24±0.20(Predicted)
optical activity: [α]20/D +70°, c = 0.2 in chloroform

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26
WGK Germany: 3
HS Code: 2906290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 494194
Product name: (S)-(+)-1-(2-Chlorophenyl)-1,2-ethanediol
Purity: 96%
Packaging: 1g
Price: $49.9
Updated: 2023/06/20

TRC

Product number: C596848
Product name: (S)-(+)-1-(2-Chlorophenyl)-1,2-ethanediol
Packaging: 50mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C596848
Product name: (S)-(+)-1-(2-Chlorophenyl)-1,2-ethanediol
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149258
Product name: (1S)-1-(2-Chlorophenyl)ethane-1,2-diol
Packaging: 250mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: X3149
Product name: (1S)-1-(2-Chlorophenyl)ethane-1,2-diol
Packaging: 1g
Price: $107
Updated: 2021/12/16

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(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL Chemical Properties,Usage,Production

Uses

o-Chlorophenyl glycol is an organic intermediate that can be obtained by oxidizing 2-chlorostyrene with hydrogen peroxide in the presence of a Cr-Anderson type polyacid modified by the catalyst (S)-1-(2-hydroxy-1-phenylethyl)thiourea.

Chemical Properties

white to beige crystals and / or chunks

Synthesis

34966-49-9

32345-65-6

General procedure for the synthesis of (R)-1-(2-chlorophenyl)-1,2-ethanediol from methyl 2-(2-chlorophenyl)-2-oxoacetate: In an inert atmosphere glove box, the substrate methyl 2-(2-chlorophenyl)-2-oxoacetate (0.5 mmol), base (0.05 mmol), Ru-MACHO catalyst (5 μmol) and methanol (0.5 mL). The glass reactor was sealed and transferred to an autoclave, followed by replacing the air in the kettle with hydrogen three times. The reaction was carried out at 25°C or 80°C with constant stirring for 12-24 h under 10-50 bar hydrogen pressure. Upon completion of the reaction, the autoclave was cooled to room temperature. The residual hydrogen was slowly released in a fume hood and the reaction mixture was transferred to a conical flask containing deionized water (2 mL) and extracted with ethyl acetate (3 x 5 mL). The organic phases were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the pure target product (R)-1-(2-chlorophenyl)-1,2-ethanediol.

References

[1] Synlett, 2016, vol. 27, # 11, p. 1748 - 1752
[2] Green Chemistry, 2012, vol. 14, # 5, p. 1372 - 1375

(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL Suppliers

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View Lastest Price from (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (1S)-1-(2-Chlorophenyl)-1,2-ethanediol 133082-13-0
Price: US $1.10-9.90/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-18

Career Henan Chemical Co

Product: (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL 133082-13-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

133082-13-0, (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOLRelated Search:

1-(4-chlorophenyl)ethane-1,2-diol 1,2-Diphenyl-1,2-bis(4-chlorophenyl)ethane-1,2-diol 1,1,2,2-Tetra(4-chlorophenyl)ethane-1,2-diol,1,1,2,2-Tetrakis(4-chlorophenyl)ethane-1,2-diol 4-CHLORO-2-[2-(2,4-DICHLORO-PHENYL)-[1,3]DIOXOLAN-2-YLMETHOXY]-BENZOTHIAZOLE 2,2'-DICHLOROBENZILIC ACID [2-(2,4-DICHLOROPHENYL)-[1,3]DIOXOLAN-2-YL]METHANOL Losigamone cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL (S)-2-HYDROXY-2-METHYL(2-CHLOROBENZENE)ACETIC ACID (S)-2-Chloromandelic acid

(S)-2-(2-CHLOROPHENYL)ETHANE-1,2-DIOL

(S)-(+)-1-(2-CHLOROPHENYL)-1,2-ETHANEDIOL

(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL

(S)-(+)-1-(2-CHLOROPHENYL)-1 2- &

(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL 95%

(1S)-1-(2-Chlorophenyl)ethane-1,2-diol,95%

(1S)-1-(2-Chlorophenyl)-1,2-ethanediol

(1S)-1-(2-Chlorophenyl)ethane-1,2-diol l

(1S)-1-(2-ChL

1,2-Ethanediol, 1-(2-chlorophenyl)-, (1S)-

(S)-1-(2-chlorophenyl)ethane-1,2-diol

(<i>S</i>)-(+)-1-(2-Chlorophenyl)-1,2-ethanediol

133082-13-0

C8H9ClO2

ClC6H4CHOHCH2OH

Asymmetric Synthesis

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