Benazolin Property

Melting point:

192-196°C

Boiling point:

468.4±55.0 °C(Predicted)

Density 

1.3274 (rough estimate)

refractive index 

1.6300 (estimate)

Flash point:

100 °C

storage temp. 

0-6°C

pka

3.50±0.10(Predicted)

color 

White, crystalline solid

Water Solubility 

0.6g/L(20 ºC)

CAS DataBase Reference

3813-05-6(CAS DataBase Reference)

EPA Substance Registry System

Benazolin (3813-05-6)

Safety

Hazard Codes 

Xi;N,N,Xi

Risk Statements 

36/38-52/53

Safety Statements 

22-61

RIDADR 

UN 3077

RTECS 

AF9700000

HS Code 

29342000

Toxicity

LD50 orl-rat: 3000 mg/kg 85ARAE 2,26,77

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

Benazolin Chemical Properties,Usage,Production

Uses

Benazolin is a selective systemic herbicide developed in the 1960s that has growth-regulatory action in susceptible plants. Structurally, it is a benzothiazolacetic acid and is unrelated to the four major groups of synthetic auxins discussed thus far. Benazolin controls a range of annual broadleaf weeds in alfalfa (Medicago sativa), canola (Brassica spp.), cereals, clover (Trifolium spp.), corn (Zea mays), grassland, and flax (Linum usitatissimum), and it has a relatively low persistence in the environment.

Definition

ChEBI: A member of the class of benzothiazoles that is 4-chloro-1,3-benzothiazol-2(3H)-one which is substituted on the nitrogen by a carboxymethyl group and at position 4 by chlorine. A post-emergence herbicide used (generally as a salt or este ) for the control of annual weeds in wheat and oilseed rape. It is not approved for use with the European Union.

Safety Profile

Moderately toxic by ingestion. Anherbicide. When heated to decomposition it emits toxicfumes of SOx, Cl^-, and NOx.

Metabolism

Because benazolin is not degraded by light and is not readily volatilized, the most important factors affecting its persistence in the environment are microbial breakdown and leaching. However, because the microbial breakdown is so rapid, significant leaching may not occur unless the rainfall within a few days of application is large.

Toxicity evaluation

Benazolin is primarily excreted in the urine as N-[2-chloro-6-(methylsulfinyl)phenyl]glycine and N-[N-[2-chloro-6-(methylthio)phenyl]glycinyl]aniline. Acid-labile conjugates of benazolin acid and N-[2-chloro- 6-(methylthio)phenylglycine] are also formed in small amounts. The acute oral LD₅₀ for rat and mice are >5000 mg/kg and >4000 mg/kg, respectively. See Table 21 for a list of toxicological data for benazolin.