ChemicalBook > CAS DataBase List > 4-HYDROXYESTRONE

4-HYDROXYESTRONE

Product Name
4-HYDROXYESTRONE
CAS No.
3131-23-5
Chemical Name
4-HYDROXYESTRONE
Synonyms
4-OH-E1;4-HYDROXYESTRONE;Estrone Impurity 8;Estrone 4-Hydroxy Impurity;1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE;1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE;5(10)-trien-17-one,3,4-dihydroxy-estra-3;3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE;3,4-dihydroxyestra-1,3,5(10)-trien-17-one;3,4-Dihydroxyestra-1(10),2,4-triene-17-one
CBNumber
CB4353324
Molecular Formula
C18H22O3
Formula Weight
286.37
MOL File
3131-23-5.mol
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4-HYDROXYESTRONE Property

Melting point:
260-263°C
Boiling point:
468.2±45.0 °C(Predicted)
Density 
1.241±0.06 g/cm3(Predicted)
Flash point:
93 °C
storage temp. 
−20°C
solubility 
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
10.06±0.40(Predicted)
color 
Pale Yellow to Light Brown
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Safety

WGK Germany 
3
RTECS 
KG7749500
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H6012
Product name
4-Hydroxyestrone
Purity
≥90% (HPLC)
Packaging
5mg
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
H6012
Product name
4-Hydroxyestrone
Purity
≥90% (HPLC)
Packaging
25mg
Price
$956
Updated
2024/03/01
TRC
Product number
H941950
Product name
4-HydroxyEstrone
Packaging
5mg
Price
$130
Updated
2021/12/16
TRC
Product number
H941950
Product name
4-HydroxyEstrone
Packaging
50mg
Price
$870
Updated
2021/12/16
Usbiological
Product number
279091
Product name
4-Hydroxy estrone
Packaging
1mg
Price
$425
Updated
2021/12/16
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4-HYDROXYESTRONE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Estradiol.

Definition

ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.

Hazard

A reproductive hazard.

Biochem/physiol Actions

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.

4-HYDROXYESTRONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYESTRONE Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 4-HYDROXYESTRONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-HYDROXYESTRONE 3131-23-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-07

3131-23-5, 4-HYDROXYESTRONERelated Search:


  • 1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE
  • 1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE
  • 3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE
  • 4-HYDROXYESTRONE
  • 3,4-dihydroxyestra-1,3,5(10)-trien-17-one
  • 5(10)-trien-17-one,3,4-dihydroxy-estra-3
  • (9S,14S)-3,4-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
  • Estrone 4-Hydroxy Impurity
  • 3,4-Dihydroxy-1(10),2,4-estratriene-17-one
  • 3,4-Dihydroxyestra-1(10),2,4-triene-17-one
  • 4-OH-E1
  • Estra-1,3,5(10)-trien-17-one, 3,4-dihydroxy-
  • Estrone Impurity 8
  • (8R,9S,13S,14S)-3,4-Dihydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one
  • 3131-23-5
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids