DESETHYL CHLOROQUINE

Product Name: DESETHYL CHLOROQUINE
CAS No.: 1476-52-4
Chemical Name: DESETHYL CHLOROQUINE
Synonyms: WR 29623;NSC 13254;Deethylchloroquine;DESETHYL CHLOROQUINE;Chloroquine USP RC D;Monodeethylchloroquine;Monodesethylchloroquine;Desethyl Chloroquine sulfate;Chloroquine Related CoMpound D;Hydroxy Chloroquine Impurity-D
CBNumber: CB4359078
Molecular Formula: C16H22ClN3
Formula Weight: 291.82
MOL File: 1476-52-4.mol

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DESETHYL CHLOROQUINE Property

Melting point:: 94-97?C
Boiling point:: 173-175 °C(Press: 0.05 Torr)
Density: 1.138±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form: Solid
pka: 10.62±0.19(Predicted)
color: Pale Yellow to Dark Yellow
biological source: synthetic

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Safety

WGK Germany: 3
HS Code: 2933497050

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00963
Product name: Desethylchloroquine
Purity: ≥95% (HPLC), research grade
Packaging: 5 mg
Price: $464
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB00963
Product name: Desethylchloroquine
Purity: ≥95% (HPLC), research grade
Packaging: 25 mg
Price: $993
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR3277
Product name: Chloroquine Related Compound D
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 40MG
Price: $802
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1118350
Product name: Chloroquine Related Compound D
Packaging: 15mg
Price: $1200
Updated: 2025/07/31

Cayman Chemical

Product number: 30113
Product name: Desethylchloroquine
Packaging: 1mg
Price: $121
Updated: 2024/03/01

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DESETHYL CHLOROQUINE Chemical Properties,Usage,Production

Chemical Properties

DESETHYL CHLOROQUINE is Tan Solid

Uses

Desethyl Chloroquine is the major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria. It is a COVID19-related research product.

Definition

ChEBI: Desethylchloroquine is an aminoquinoline.

in vivo

Intraperitoneal injections of Chloroquine are administered to wild-type and Huntington's disease (Q175/Q175) mice. LC-MS/MS is used to compare the levels Chloroquine and its metabolites in blood, brain and muscle tissue. Concentrations of Chloroquine are lower (5-15M), but more stable in brain tissue compared to blood or muscle between 4 and 24 hours after the last dose. Levels of the active Chloroquine metabolite Desethyl chloroquine decreased in muscle and blood over the 24 hour post-injection period, while brain Desethyl chloroquine levels are lower and rose slightly over the same time frame^[3].

IC 50

Plasmodium; TLRs

DESETHYL CHLOROQUINE Preparation Products And Raw materials

Raw materials

Preparation Products

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DESETHYL CHLOROQUINE Suppliers

Canada 2 China 89 India 5 United Kingdom 2 United States 12 Global 110

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Chemsky（shanghai）International Co.,Ltd.

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Daicel Chiral Technologies (China)CO.,LTD

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Artis Chemistry (Shanghai) Co. Ltd.

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S.Z. PhyStandard Bio-Tech. Co., Ltd.

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ChemStrong Scientific Co.,Ltd

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Shanghai Kewel Chemical Co., Ltd.

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BOC Sciences

Tel: 16314854226
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1476-52-4, DESETHYL CHLOROQUINERelated Search:

Desethyl Chloroquine-d4 LABOTEST-BB LT00452833 CHLOROQUINE DESETHYL HYDROXY CHLOROQUINE 6-Amino-7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline di phosphate Mepacrine hydrochloride DESETHYL CHLOROQUINE Hydroxychloroquine ICR 386 QUINACRINE MUSTARD DIHYDROCHLORIDE Chloroquine diphosphate Aminoquinol Hydroxychloroquine sulfate CHLOROQUINE-[3H(G)] 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-6-nitroquinoline di phosphate Chloroquine sulfate

DESETHYL CHLOROQUINE

Deethylchloroquine

Desethyl Chloroquine DiHBr (Hydroxychloroquine Sulfate EP Impurity D DiHBr)

Hydroxychloroquine Sulfate EP Impurity D DiHBr

Chloroquine Impurity 1（Desethyl Chloroquine）

Hydroxychloroquine Sulfate Impurity 4（Hydroxychloroquine Sulfate EP Impurity D）

Hydroxychloroquine Impurity 9 2HBr

Monodeethylchloroquine

N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine

NSC 13254

WR 29623

4-[[1-Methyl-4-(ethylamino)butyl]amino]-7-chloroquinoline

N'-(7-Chloroquinolin-4-yl)-N-ethyl-1,4-pentanediamine

N-[1-Methyl-4-(ethylamino)butyl]7-chloro-4-quinolinamine

N-[4-(Ethylamino)-1-methylbutyl]-7-chloroquinoline-4-amine

(7-chloro-4-quinolyl)-[4-(ethylamino)-1-methyl-butyl]amine

4-N-(7-chloroquinolin-4-yl)-1-N-ethylpentane-1,4-diamine

N4-(7-chloroquinolin-4-yl)-N1-ethyl-pentane-1,4-diamine

Chloroquine Related CoMpound D

7-Chloro-4-{[4-(ethylamino)-1-methylbutyl]amino}quinoline

Monodesethylchloroquine

Desethyl Chloroquine sulfate

Hydroxychloroquine EP Impurity D/Desethyl Chloroquine

Chloroquine USP RC D

1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1-ethyl-

Desethyl Chloroquine (Hydroxychloroquine EP Impurity D)

(4RS)-N4-(7-Chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine

Chloroquine Related Compound D (7-Chloro-4-{[4-(ethylamino)-1-methylbutyl] amino} quinoline) (1118350)

Desethyl Chloroquine HBr (Hydroxychloroquine Sulfate EP Impurity D HBr)

Hydroxychloroquine Sulfate EP Impurity D (Desethyl Chloroquine)

Chloroquine USP Related Compound-D

Clavulanate Potassium Impurity 20 Monomer

Hydroxy Chloroquine Impurity-D

Hydroxychloroquine Sulfate EP Impurity D (Chloroquine USP Related Compound D, Desethyl Chloroquine)

1476-52-4

1476-52-5

C16H22ClN3

Metabolite

Various Metabolites and Impurities

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals