DESETHYL HYDROXY CHLOROQUINE

Product Name: DESETHYL HYDROXY CHLOROQUINE
CAS No.: 4298-15-1
Chemical Name: DESETHYL HYDROXY CHLOROQUINE
Synonyms: cletoquine;2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol;Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol;Cletoquine, 10 mM in DMSO;DESETHYL HYDROXY CHLOROQUINE;Desethyl Hydroxy Chloroquine DiHCl;Desethylhydroxychloroquine Dihydroc;Hydroxychloroquine Sulphate Impurity 9;Hydroxychloroquine Sulfate EP Impurity C;Hydroxychloroquine EP Impurity C (Phosphate)
CBNumber: CB0286433
Molecular Formula: C16H22ClN3O
Formula Weight: 307.82
MOL File: 4298-15-1.mol

More

Less

DESETHYL HYDROXY CHLOROQUINE Property

Melting point:: 112-115°C
Boiling point:: 514.7±50.0 °C(Predicted)
Density: 1.212±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka: 14.80±0.10(Predicted)
form: Solid
color: Off-White to Yellow
Stability:: Hygroscopic
InChI: InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)
InChIKey: XFICNUNWUREFDP-UHFFFAOYSA-N
SMILES: C(O)CNCCCC(NC1C2C(N=CC=1)=CC(Cl)=CC=2)C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

More

Less

N-Bromosuccinimide Price

TRC

Product number: C573505
Product name: Cletoquine
Packaging: 25mg
Price: $2725
Updated: 2021/12/16

AK Scientific

Product number: 4392CA
Product name: Cletoquine
Packaging: 1mg
Price: $436
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000483
Product name: CLETOQUINE
Purity: 95.00%
Packaging: 5MG
Price: $495.8
Updated: 2021/12/16

More

Less

DESETHYL HYDROXY CHLOROQUINE Chemical Properties,Usage,Production

Uses

Cletoquine is a metabolite of Hydroxychloroquine (H916900), an antimalarial; antirheumatic; lupus erythematosus suppressant.

in vivo

Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine (Desethylhydroxychloroquine). The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)^[3].

DESETHYL HYDROXY CHLOROQUINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DESETHYL HYDROXY CHLOROQUINE Suppliers

Canada 1 China 98 China Hong Kong 1 India 7 United Kingdom 1 United States 11 Global 119

Zhengzhou Ruike Biochemical Technology Co., Ltd.

Tel: 18521304688
Email: 421551521@qq.com
Country: China
ProdList: 267
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7938
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 7048
Advantage: 58

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1961
Advantage: 58

Shanghai YuZn Pharm. Technology Co.,Ltd.

Tel: 15921286451; 15921286451
Email: 2010681527@qq.com
Country: China
ProdList: 5182
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7471
Advantage: 65

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

4298-15-1, DESETHYL HYDROXY CHLOROQUINERelated Search:

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol Hydroxychloroquine O-Sulfate Linagliptin Impurity D Linagliptin Impurity K Linagliptin iMpurity G 8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate Linagliptin iMpurity E Hydroxychloroquine Sulfate EP Impurity A Linagliptin Impurity F BISDESETHYL CHLOROQUINE Hydroxychloroquine sulfate Hydroxychloroquine CHLOROQUINE DESETHYL HYDROXY CHLOROQUINE DESETHYL CHLOROQUINE 4-(4-AMINOBUT-1-YL)AMINOQUINOLINE 4-(4-AMINOBUTYL)AMINO-7-CHLOROQUINOLINE

2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol

2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol

Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol

DESETHYL HYDROXY CHLOROQUINE

cletoquine

Hydroxychloroquine Sulfate Impurity 3（Hydroxychloroquine Sulfate EP Impurity C）

Hydroxychloroquine Sulfate EP Impurity C (Desethyl Hydroxy Chloroquine)

Desethyl Hydroxy Chloroquine DiHCl

Hydroxychloroquine Sulfate EP Impurity C

Desethylhydroxychloroquine Dihydroc

Hydroxychloroquine EP Impurity C (Phosphate)

Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-

Hydroxychloroquine Sulphate Impurity 9

Hydroxychloroquine EP Impurity C (Cletoquine)

2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol

Ndesethylation,inhibit,CHIKV,P23pro-zbd,Parasite,antimalarial,CYP2D6,Influenza Virus,CYP3A4,CYP2C8,CYP3A5,Inhibitor,Hydroxychloroquine,antiviral

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)amino)ethan-1-ol

Cletoquine, 10 mM in DMSO

4298-15-1

420.98-15-1

Metabolite

API