ChemicalBook > CAS DataBase List > DESETHYL HYDROXY CHLOROQUINE

DESETHYL HYDROXY CHLOROQUINE

Product Name: DESETHYL HYDROXY CHLOROQUINE
CAS No.: 4298-15-1
Chemical Name: DESETHYL HYDROXY CHLOROQUINE
Synonyms: cletoquine;2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol;Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol;Cletoquine, 10 mM in DMSO;DESETHYL HYDROXY CHLOROQUINE;Desethyl Hydroxy Chloroquine DiHCl;Desethylhydroxychloroquine Dihydroc;Hydroxychloroquine Sulphate Impurity 9;Hydroxychloroquine Sulfate EP Impurity C;Hydroxychloroquine EP Impurity C (Phosphate)
CBNumber: CB0286433
Molecular Formula: C16H22ClN3O
Formula Weight: 307.82
MOL File: 4298-15-1.mol

Less

DESETHYL HYDROXY CHLOROQUINE Property

Melting point:: 112-115°C
Boiling point:: 514.7±50.0 °C(Predicted)
Density: 1.212±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka: 14.80±0.10(Predicted)
form: Solid
color: Off-White to Yellow
Stability:: Hygroscopic
InChI: InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)
InChIKey: XFICNUNWUREFDP-UHFFFAOYSA-N
SMILES: C(O)CNCCCC(NC1C2C(N=CC=1)=CC(Cl)=CC=2)C

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

Less

N-Bromosuccinimide Price

TRC

Product number: C573505
Product name: Cletoquine
Packaging: 25mg
Price: $2725
Updated: 2021/12/16

AK Scientific

Product number: 4392CA
Product name: Cletoquine
Packaging: 1mg
Price: $436
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000483
Product name: CLETOQUINE
Purity: 95.00%
Packaging: 5MG
Price: $495.8
Updated: 2021/12/16

Less

DESETHYL HYDROXY CHLOROQUINE Chemical Properties,Usage,Production

Uses

Cletoquine is a metabolite of Hydroxychloroquine (H916900), an antimalarial; antirheumatic; lupus erythematosus suppressant.

in vivo

Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine (Desethylhydroxychloroquine). The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)^[3].

DESETHYL HYDROXY CHLOROQUINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

DESETHYL HYDROXY CHLOROQUINE Suppliers

Canada 1 China 98 China Hong Kong 1 India 7 United Kingdom 1 United States 11 Global 119

Zhengzhou Ruike Biochemical Technology Co., Ltd.

Tel: 18521304688
Email: 421551521@qq.com
Country: China
ProdList: 267
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7936
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 7047
Advantage: 58

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1961
Advantage: 58

Shanghai YuZn Pharm. Technology Co.,Ltd.

Tel: 15921286451; 15921286451
Email: 2010681527@qq.com
Country: China
ProdList: 5181
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7471
Advantage: 65

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Shanghai Famo Bio-chemical Technology Company Ltd.

Tel: 021-02136680027 15800370750
Email: 1706640024@qq.com
Country: China
ProdList: 570
Advantage: 56

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shandong Boluoda Biological Technology Co., Ltd.

Tel: 0531-68652053 15863796298;
Email: 2310993908@qq.com
Country: China
ProdList: 2437
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4855
Advantage: 55

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10410
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Wellman Pharmaceutical Group Limited

Tel: 027-027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 3932
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9748
Advantage: 58

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: 021-58958618
Email: sales@uhnshanghai.com
Country: China
ProdList: 1984
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9852
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 13316949107 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 9564
Advantage: 58

Hefei Molake Biotechnology Co., Ltd.

Tel: 0551-66336380 18956014586
Fax: 055166336380
Email: 983438788@qq.com
Country: China
ProdList: 2297
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7924
Advantage: 58

Shanghai Fuyi Biological Technology Co., Ltd.

Tel: 18096642264
Email: sales@foreversyn.com
Country: China
ProdList: 492
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15107
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 19925672674
Fax: QQ 3008233717
Email: 3008233746@qq.com
Country: China
ProdList: 9883
Advantage: 12

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Yangzhou Changhua Biotechnology Co., Ltd.

Tel: 15189846850 13815846020
Email: 710163098@qq.com
Country: China
ProdList: 909
Advantage: 58

Tianjin shijia biomedical technology co., LTD

Tel: 15022261580 15022261580;
Email: tjshj1212@163.com
Country: China
ProdList: 2745
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shenzhen ruikai de biotechnology co., ltd.

Tel: 0755-61348847 17820674378
Fax: 0755-21016893
Email: 2682116078@qq.com
Country: China
ProdList: 7843
Advantage: 58

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7587
Advantage: 58

Wuhan Dingtong Pharmaceutical Co., Ltd

Tel: 027-027-59207795 18327179646
Fax: 027-59207795
Email: 18327179646@163.com
Country: China
ProdList: 1986
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-029-81024372 17792795018
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 9997
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10001
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Shanghai Xuanlin Pharmaceutical Technology Co., Ltd

Tel: 13955239259
Fax: QQ3450014153 ;
Email: 3295742260@qq.com
Country: China
ProdList: 976
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7984
Advantage: 58

Hubei Wande Chemical Co., Ltd

Tel: 027-027-59210159 15377098680
Fax: 027-59210159
Email: 1148280011@qq.com
Country: China
ProdList: 9835
Advantage: 58

4298-15-1, DESETHYL HYDROXY CHLOROQUINERelated Search:

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol Hydroxychloroquine O-Sulfate Linagliptin Impurity D Linagliptin Impurity K Linagliptin iMpurity G 8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate Linagliptin iMpurity E Hydroxychloroquine Sulfate EP Impurity A Linagliptin Impurity F BISDESETHYL CHLOROQUINE Hydroxychloroquine sulfate Hydroxychloroquine CHLOROQUINE DESETHYL HYDROXY CHLOROQUINE DESETHYL CHLOROQUINE 4-(4-AMINOBUT-1-YL)AMINOQUINOLINE 4-(4-AMINOBUTYL)AMINO-7-CHLOROQUINOLINE

2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol

2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol

Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol

DESETHYL HYDROXY CHLOROQUINE

cletoquine

Hydroxychloroquine Sulfate Impurity 3（Hydroxychloroquine Sulfate EP Impurity C）

Hydroxychloroquine Sulfate EP Impurity C (Desethyl Hydroxy Chloroquine)

Desethyl Hydroxy Chloroquine DiHCl

Hydroxychloroquine Sulfate EP Impurity C

Desethylhydroxychloroquine Dihydroc

Hydroxychloroquine EP Impurity C (Phosphate)

Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-

Hydroxychloroquine Sulphate Impurity 9

Hydroxychloroquine EP Impurity C (Cletoquine)

2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol

Ndesethylation,inhibit,CHIKV,P23pro-zbd,Parasite,antimalarial,CYP2D6,Influenza Virus,CYP3A4,CYP2C8,CYP3A5,Inhibitor,Hydroxychloroquine,antiviral

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)amino)ethan-1-ol

Cletoquine, 10 mM in DMSO

4298-15-1

420.98-15-1

Metabolite

API