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MILBEMECTIN A3

Product Name
MILBEMECTIN A3
CAS No.
51596-10-2
Chemical Name
MILBEMECTIN A3
Synonyms
milbemycin;Milbemycin α1;milbemycin A3;milbemycinb-2;MILBEMECTIN A3;milbemectine a3;Antibiotic B-41A3;Milbemycin oxime A3;Milbemycin EP Imp B;Milbemite Impurity 1
CBNumber
CB4359654
Molecular Formula
C31H44O7
Formula Weight
528.69
MOL File
51596-10-2.mol
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MILBEMECTIN A3 Property

Melting point:
212-215°; mp 192-194°
alpha 
D20 +106° (c = 0.25 in acetone) (Aoki); D20 +106° (acetone) (Hirama)
Boiling point:
725.5±60.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
0-6°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
12.46±0.70(Predicted)
color 
White to light yellow
InChIKey
ZLBGSRMUSVULIE-HIKHPYAJNA-N
EPA Substance Registry System
Milbemycin A3 (51596-10-2)
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Safety

RIDADR 
2588
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18360
Product name
Milbemycin A3
Purity
≥95%
Packaging
1mg
Price
$326
Updated
2024/03/01
Cayman Chemical
Product number
18360
Product name
Milbemycin A3
Purity
≥95%
Packaging
5mg
Price
$977
Updated
2024/03/01
Usbiological
Product number
M3896-80
Product name
Milbemycin A3
Packaging
1mg
Price
$561
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0016453
Product name
MILBEMYCIN ALPHA3
Purity
95.00%
Packaging
5MG
Price
$503.09
Updated
2021/12/16
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MILBEMECTIN A3 Chemical Properties,Usage,Production

Description

Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 against adult spider mites, spider mite eggs, and C. elegans are reported at IC50 values of 5.3, 41.1, and 9.5 μg/ml.

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is a major member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

Uses

Milbemycin A3 is widely used as a pesticides in agriculture. Milbemycin A3 (Milbemycin EP Impurity B) is an antibiotic with acaricidal activity.

Definition

ChEBI: Milbemycin A3 is a milbemycin.

References

[1] LING-YU YANG . New nemadectin congeners with acaricidal and nematocidal activity from Streptomyces microflavus neau3 Y-3[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23 20: Pages 5710-5713. DOI: 10.1016/j.bmcl.2013.08.002

MILBEMECTIN A3 Preparation Products And Raw materials

Raw materials

Preparation Products

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MILBEMECTIN A3 Suppliers

China 65 France 1 Germany 1 India 3 Japan 1 United Kingdom 1 United States 9 Global 81
Huzhou fuhe Rui biological medicine co., ltd
Tel
13626726938
Country
China
ProdList
791
Advantage
58
SHANG HAI WEI LING BIOTECHNOLOGY CO.,LTD
Tel
021-13917490980 13917490980
Email
81939905@qq.com
Country
China
ProdList
488
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 0086-15250997978
Fax
025-58362220
Email
sale@njxizebio.com
Country
China
ProdList
4855
Advantage
55
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
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View Lastest Price from MILBEMECTIN A3 manufacturers

Moxin Chemicals
Product
Milbemycin Oxime EP Impurity B 51596-10-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98
Supply Ability
10000000
Release date
2025-02-24

51596-10-2, MILBEMECTIN A3Related Search:

MilbeMycin A3 OxiMe MilbeMycin A4 OxiMe MILBEMECTIN A4 Miconazole IMpurity B MILRINONE RELATED COMPOUND A (50 MG) (1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CAR-BOXAMIDE) 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxylic acid 1,6-Dihydro-2-(hydroxyMethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile Milbemycin oxime Isoconazole Milbemycin EP Impurity D Milrinone Impurity 13 Miconazole Impurity Miconazole IMpurity I 5-Decyano 5-(Ethyl Formate) Milrinone Milrinone Impurity 17 Milrinone Impurity 14 Milbemycin EP Impurity E Miconazole EP Impurity E

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  • (25R)-25-Methyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B
  • Milbemycin oxime A3
  • (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B
  • Antibiotic B-41A3
  • Milbemycin α1
  • (+)-Chloropseudoephedrine (hydrochloride)
  • B 41A3, MilbeMycin alpha1, MilbeMectin
  • Milbemycin EP Impurity B
  • Milbemycin Impurity 2(Milbemycin EP Impurity B)
  • Milbemycin EP Imp B
  • Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-, (6R,25R)-
  • Milbemite Impurity 1
  • Milbemycin Oxime EP Impurity B
  • Milbemectin A3 10.0 μg/ml Acetonitrile
  • Milbemectin A3 10 μg/mL in Acetonitrile
  • (2R,2a'E,2a1'S,4'E,5S,6R,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-5,6,6',8',19'-pentamethyl-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one
  • 51596-10-2
  • 51596-20-2
  • C31H44O7