3-Ethoxy-1-propanol Property

Melting point:

-90°C (estimate)

Boiling point:

160-161 °C(lit.)

Density 

0.904 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.417(lit.)

Flash point:

130 °F

pka

14.90±0.10(Predicted)

Specific Gravity

0.904

Odor

fruit

Water Solubility 

>=10 g/100 mL at 18 º

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents.

CAS DataBase Reference

111-35-3(CAS DataBase Reference)

NIST Chemistry Reference

1-Propanol, 3-ethoxy-(111-35-3)

EPA Substance Registry System

3-Ethoxy-1-propanol (111-35-3)

Safety

Hazard Codes 

Xn

Risk Statements 

10-20/21/22-36

Safety Statements 

16-26-36/37/39

RIDADR 

UN 1987 3/PG 3

WGK Germany 

3

RTECS 

UB5075000

HazardClass 

3.2

PackingGroup 

III

HS Code 

2909498090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

3-Ethoxy-1-propanol Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

3-??Ethoxy-??1-??propanol is used in the synthesis of [1,2,4]triazolo[1,5-a]pyrimidines as anticancer agents. It is also used to prepare N-substituted [(carboxymethyl)phenoxy]ethyl benzoxazinones as PPARγ agonists and antidiabetic (type 2) agents.

Definition

ChEBI: A hydroxyether that is propan-1-ol substituted by an ethoxy group at position 3.

General Description

A clear colorless liquid, with a mild odor. Less dense than water. Contact may slightly irritate skin, eyes and mucous membranes.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

3-Ethoxy-1-propanol is an ethoxy-alcohol derivative. The ether is relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

3-Ethoxy-1-propanol is combustible.