ChemicalBook > CAS DataBase List > Rafoxanide

Rafoxanide

Product Name
Rafoxanide
CAS No.
22662-39-1
Chemical Name
Rafoxanide
Synonyms
N-[3-chloro-4-(4-chlorophenoxy)phenyl]-3,5-diiodobenzamide;duofas;mk-990;Ranide;Disalan;Rezonit;bovanide;flukanide;RAFOXANIDE;rafoxanidum
CBNumber
CB4374963
Molecular Formula
C19H11Cl2I2NO3
Formula Weight
626.01
MOL File
22662-39-1.mol
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Rafoxanide Property

Melting point:
168-170°
Boiling point:
526.6±50.0 °C(Predicted)
Density 
2.050±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka
6.04±0.48(Predicted)
form 
Solid
color 
White to Off-White
Merck 
14,8097
InChI
InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
InChIKey
NEMNPWINWMHUMR-UHFFFAOYSA-N
SMILES
C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)(=O)C1=CC(I)=CC(I)=C1O
CAS DataBase Reference
22662-39-1(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
VN7870000
HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
34042
Product name
Rafoxanide
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$139
Updated
2025/07/31
TCI Chemical
Product number
R0108
Product name
Rafoxanide
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$153
Updated
2025/07/31
Cayman Chemical
Product number
29616
Product name
Rafoxanide
Packaging
250mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
29616
Product name
Rafoxanide
Packaging
500mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
29616
Product name
Rafoxanide
Packaging
1g
Price
$155
Updated
2024/03/01
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Rafoxanide Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Rafoxanide is a thyroid hormone receptor.

in vivo

Rafoxanide (7.5 mg/kg, i.p., once every 2 d for 88d) reduces colonic tumorgenesis in Apcmin/+ mice[3].

Animal Model:AOM induced Apcmin/+ mice[3]
Dosage:7.5 mg/kg
Administration:Intraperitoneal injection (i.p.), once every 2 d for 88d
Result:Exerted less number and size of AOM induced lesions in the colon. No significant body weight changes were observed.
Detected adenomas (28.6%), advanced adenomas (67.8%) and adenocarcinoma (3.6%) in control group as adenomas (33.3%), advanced adenomas (25%%) and no obvious lesions(41.6%) were detected in treated group.
Caused increased signal for p-eIF2α, CHOP and cleaved caspase-3 in tumor tissues while these signal in non-tumor colon epithelium were barely detectable.

IC 50

Schistosome

Rafoxanide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Rafoxanide manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Rafoxanide 22662-39-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-21
Hebei Chuanghai Biotechnology Co., Ltd
Product
Rafoxanide 22662-39-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Rafoxanide 22662-39-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-01

22662-39-1, RafoxanideRelated Search:


  • 3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodo-salicylanilid
  • 3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodosalicylanilide
  • bovanide
  • duofas
  • flukanide
  • Rafoxanide 0.1
  • N-[3-chloro-4-(4-chlorophenoxy)phenyl]-3,5-diiodobenzamide
  • Disalan
  • mk-990
  • n-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-benzamid
  • DIANMILIU'AN RAFOXANIDE
  • 3'-CHLORO-4'-(4-CHLOROPHENOXY)-3,5-DIIODOSALICYLANILIDE
  • RAFOXANIDE
  • rafoxanidum
  • Ranide
  • Rafoxanide BP V85
  • N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
  • 3''-CHLORO-4''-(4-CHLOROPHENOXY)-3,5-DIIODOSALICYLANILIDE(RAFOXANIDE)
  • RADIXGLYCYRRHIZAE.P.E
  • 3'-Chloro-4'-(p-chlorophenoxy)-2-hydroxy-3,5-diiodobenzanilide
  • Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-
  • N-[3-Chloro-4-(4-chlorophepoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
  • 3,5-Diiodo-3'-chloro-4'-(p-chlorophenoxy)salicylanilide
  • 3,5-Diodo-3'-chloro-4'- (p-chlorophenoxy)salicylanilide
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  • Iodine ether salicylate
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  • 22662-39-1