PDDHV

Product Name: PDDHV
CAS No.: 179469-40-0
Chemical Name: PDDHV
Synonyms: PDDHV;PHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE;Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9,9a-bis[(1-oxodecyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methyl ester
CBNumber: CB4381723
Molecular Formula: C49H72O11
Formula Weight: 837.09
MOL File: 179469-40-0.mol

More

Less

PDDHV Property

storage temp.: −20°C
solubility: Methanol: soluble
form: A solid

More

Less

Safety

Hazard Codes: T+
Risk Statements: 26/27/28-36/37/38
Safety Statements: 26-27-36/37/39-45
RIDADR: UN 2811 6.1/PG 2

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 20445
Product name: PDDHV
Purity: ≥99%
Packaging: 1mg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 20445
Product name: PDDHV
Purity: ≥99%
Packaging: 5mg
Price: $191
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008544
Product name: PHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE
Purity: 95.00%
Packaging: 1MG
Price: $151.2
Updated: 2021/12/16

AK Scientific

Product number: 9070CR
Product name: Pddhv
Packaging: 1mg
Price: $160
Updated: 2021/12/16

More

Less

PDDHV Chemical Properties,Usage,Production

Description

PDDHV is a resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1. It induces Ca²⁺-uptake by rat dorsal root ganglion neurons with an EC₅₀ value of 70 nM.

Uses

PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats[1].

References

[1] Szallasi A, Szabo T, Biro T, et al. Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1[J]. British journal of pharmacology, 1999, 128(2): 428-434.

PDDHV Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PDDHV Suppliers

China 21 Switzerland 3 United Kingdom 2 United States 3 Global 29

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

179469-40-0, PDDHVRelated Search:

ALLYL PHENYLACETATE ETHYL HOMOVANILLATE 2,5-DIMETHYL-2-HEXENE-1,6-DIOL DIACETATE PHENYLACETIC ACID TRANS-2-HEXEN-1-YL ESTER PDDHV PHORBOL 12,13-DIDECANOATE PDNHV PHORBOL 12,13-DIACETATE ETHYL 3,4-DIHYDROXYPHENYLACETATE PHORBOL-12-DECANOATE PHORBOL-12,13-DIHEXANOATE PHORBOL 12,13-DIBUTYRATE PHORBOL 12,13,20-TRIACETATE, 4BETA phorbol-12,13-dipropionate PHORBOL 13,20-DIACETATE 1,2-Dimethyl-1,2-ethanediyl decanoate 12-deoxyphorbol-13-decanoate 12-O-acetylphorbol-13-decanoate

PHORBOL 12,13-DIDECANOATE 20-HOMOVANILLATE

PDDHV

Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9,9a-bis[(1-oxodecyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methyl ester

179469-40-0

C49H72O11