ALPHA-HEMOLYSIN
- Product Name
- ALPHA-HEMOLYSIN
- CAS No.
- 94716-94-6
- Chemical Name
- ALPHA-HEMOLYSIN
- Synonyms
- α-HeMolysin;ALPHA-TOXIN;ALPHA-HEMOLYSIN;STAPHYLOCOCCUS AUREUS;Staphylococcus piscifermentans;ALPHA-TOXIN, STAPHYLOCOCCUS AUREUS;α-HemolysinfromStaphylococcusaureus;α-Hemolysin (Staphylococcus aureus);α-hemolysin from staphylococcus aureus;A-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
- CBNumber
- CB4384087
- Formula Weight
- 0
- MOL File
- Mol file
ALPHA-HEMOLYSIN Property
- storage temp.
- 2-8°C
- solubility
- H2O: soluble0.49 - 0.51mg/mL
- form
- lyophilized powder
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H371May cause damage to organs
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H9395
- Product name
- α-Hemolysin from Staphylococcus aureus
- Purity
- lyophilized powder, Protein ~60?% by Lowry, ≥10,000?units/mg protein
- Packaging
- 0.5MG
- Price
- $362.4
- Updated
- 2024/03/01
- Product number
- H9395
- Product name
- α-Hemolysin from Staphylococcus aureus
- Purity
- lyophilized powder, Protein ~60 % by Lowry, ≥10,000 units/mg protein
- Packaging
- 1mg
- Price
- $812
- Updated
- 2024/03/01
ALPHA-HEMOLYSIN Chemical Properties,Usage,Production
Uses
α-Hemolysin was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.
Uses
ALPHA-HEMOLYSIN was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.
General Description
α-Hemolysin, a pore-forming cytotoxin is an extracellular protein secreted by most strains of pathogenic?Staphylococcus aureus. It is secreted as a water-soluble monomer and is a small β-barrel protein.
Biochem/physiol Actions
α-Hemolysin is selectively hemolytic and the monomeric form binds to a membrane and specific receptors are not required for binding. Upon binding to biological membranes and/or artificial membranes, self-oligomerization occurs, resulting in ring structures (hexameric aggregates) believed to represent transmembrane pores, which are permeable to ions and small metabolites. It has a marked preference for rabbit red blood cells. α-hemolysin stimulates cellular phospholipases and induces a Ca2+?influx. It leads to membrane disruption of the endothelial barrier and leakage of cytoplasmic components and osmotic lysis of the cells. α-hemolysin is implicated in the pathogenesis of sepsis.