NUCIFERINE

Uses

Product Name: NUCIFERINE
CAS No.: 475-83-2
Chemical Name: NUCIFERINE
Synonyms: nuciferin;6a;VLT 049;Nuciferi;NUCIFERINE;Sanjoinine;fettuccine;l-nuciferine;Sanjoinine E;(R)-Nuciferine
CBNumber: CB4384597
Molecular Formula: C19H21NO2
Formula Weight: 295.38
MOL File: 475-83-2.mol

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NUCIFERINE Property

Melting point:: 165.5°C
Boiling point:: 437.06°C (rough estimate)
Density: 1.1156 (rough estimate)
refractive index: 1.5000 (estimate)
storage temp.: 2-8°C
solubility: DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
pka: 7.87±0.20(Predicted)
form: powder
color: white to beige
optical activity: [α]/D -145 to -165°, c = 0.5 in ethanol
LogP: 2.357 (est)

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Safety

Safety Statements: 24/25
RIDADR: UN 1544PSN1 6.1 / PGIII
HS Code: 29389090
Toxicity: LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2230
Product name: Nuciferine
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $63.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2230
Product name: Nuciferine
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $193
Updated: 2024/03/01

TCI Chemical

Product number: N1170
Product name: Nuciferine
Packaging: 250MG
Price: $672
Updated: 2024/03/01

TCI Chemical

Product number: N1170
Product name: Nuciferine
Packaging: 50MG
Price: $275
Updated: 2021/12/16

Sigma-Aldrich

Product number: PHL83282
Product name: Nuciferine
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $514
Updated: 2024/03/01

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NUCIFERINE Chemical Properties,Usage,Production

Uses

The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments.

Description

Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] ²²_D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.).

Uses

Nuciferin is an drug candidate for the treatment of obesity-related diseases. It is not well studied and its pharmacokinetics in vivo have not been fully investigated.

Safety Profile

Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.

References

Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963)

NUCIFERINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NUCIFERINE Suppliers

Americas 1 China 301 Europe 1 India 5 Japan 1 The Netherlands 1 United Kingdom 6 United States 19 USA 1 Global 336

Xi'AnTongZeBiotechCo.,Ltd

Tel: +86-18591971926 +86-18591971926
Email: 3516471159@qq.com
Country: China
ProdList: 154
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4941
Advantage: 60

Guangzhou Dihao Medical Technology Co., Ltd

Tel: 18602015453
Email: 2667751176@qq.com
Country: China
ProdList: 517
Advantage: 58

Shaanxi xintianyu Biotechnology Co., Ltd.

Tel: 029-32565555 18710500080
Email: 1064976462@qq.com
Country: China
ProdList: 689
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
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BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
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Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
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Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4550
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View Lastest Price from NUCIFERINE manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: NUCIFERINE 475-83-2
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2024-01-04

BINBO BIOLOGICAL CO.,LTD

Product: Nuciferine 475-83-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 1000 kg
Release date: 2024-04-11

Shaanxi Haibo Biotechnology Co., Ltd

Product: Nuciferine 475-83-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-09-08

475-83-2, NUCIFERINERelated Search:

PEPPERMINT Tea polyphenol Kidney Bean Extract Cassia seed extract Shikimic acid Rotundine Nicotinamide Green coffee P.E. Rimonabant Neferine Glabridin Lotus Leaf Extract PU-ERHTEAP.E. Wolfberry extract Polysaccharides 15% UV Hawthorn NUCIFERINE O-METHYLISOCORYDINE IODOMETHYLATE 7-hydroxyglaucine

(-)-nucipherine

(r)-1,2-dimethoxyaporphine

1,2-dimethoxy-6a-beta-aporphin

6a

4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-

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Nuciferine, 98%, from Lotus Leaf

professional manufacturer Nuciferine 475-83-2

Nuciferine 475-83-2

radix bupleuri P.E

5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-g)quinolin(r)-4h-dibenzo(d

l-5,6-dimethoxyaporphine

l-nuciferine

nuciferin

NUCIFERINE

1,2-Dimethoxy-6aβ-aporphine

Sanjoinine E

(6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline

1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

(R)-Nuciferine

D-(-)-Nuciferine

1,2-Dimethoxy-6αβ-aporphine

VLT 049

Sanjoinine

(R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

Lotus Leaf Extract Powder Nuciferine

NUCIFERINE USP/EP/BP

Lotus leaf alkali

Nuciferi

fettuccine

lotus leaf extract lotusine

NUCIFERINE (lotusleaf extract)

Louts Leaf Extract

1,2-Dimethoxy-6αβ-aporphine

475-83-2

standardized herbal extract

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

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