ChemicalBook > CAS DataBase List > NUCIFERINE

NUCIFERINE

Uses

Product Name: NUCIFERINE
CAS No.: 475-83-2
Chemical Name: NUCIFERINE
Synonyms: nuciferin;6a;VLT 049;Nuciferi;NUCIFERINE;Sanjoinine;fettuccine;l-nuciferine;Sanjoinine E;Nuciferine-RM
CBNumber: CB4384597
Molecular Formula: C19H21NO2
Formula Weight: 295.38
MOL File: 475-83-2.mol

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NUCIFERINE Property

Melting point:: 165.5°C
Boiling point:: 437.06°C (rough estimate)
Density: 1.1156 (rough estimate)
refractive index: 1.5000 (estimate)
storage temp.: 2-8°C
solubility: DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
pka: 7.87±0.20(Predicted)
form: powder
color: white to beige
optical activity: [α]/D -145 to -165°, c = 0.5 in ethanol
InChI: InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
InChIKey: ORJVQPIHKOARKV-OAHLLOKOSA-N
SMILES: N1(C)[C@@]2([H])C3=C(C(OC)=C(OC)C=C3CC1)C1=CC=CC=C1C2
LogP: 2.357 (est)

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Safety

Safety Statements: 24/25
RIDADR: UN 1544PSN1 6.1 / PGIII
HS Code: 29389090
Toxicity: LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2230
Product name: Nuciferine
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $55.81
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2230
Product name: Nuciferine
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $198
Updated: 2025/07/31

TCI Chemical

Product number: N1170
Product name: Nuciferine
Packaging: 250MG
Price: $605
Updated: 2025/07/31

TCI Chemical

Product number: N1170
Product name: Nuciferine
Packaging: 50MG
Price: $275
Updated: 2021/12/16

Sigma-Aldrich

Product number: PHL83282
Product name: Nuciferine
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $480
Updated: 2025/07/31

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NUCIFERINE Chemical Properties,Usage,Production

Uses

The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments.

Description

Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] ²²_D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.).

Chemical Properties

Soluble in benzene, ether, chloroform, halogenated alkanes and other organic solvents of low polarity, in acetone, ethanol and other hydrophilic organic solvents also have good solubility, but less soluble or almost insoluble in water Derived from the dried leaves of Lotus japonicus, family Water Lily

Uses

Nuciferin is an drug candidate for the treatment of obesity-related diseases. It is not well studied and its pharmacokinetics in vivo have not been fully investigated.

Safety Profile

Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.

References

Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963)

NUCIFERINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NUCIFERINE manufacturers

Shaanxi Xianhe Biotech Co., Ltd

Product: NUCIFERINE 475-83-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-27

Hebei Fengjia New Material Co., Ltd

Product: Lotus Leaf extract 475-83-2
Price: US $30.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100 tons
Release date: 2024-08-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: NUCIFERINE 475-83-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

475-83-2, NUCIFERINERelated Search:

PEPPERMINT Tea polyphenol Kidney Bean Extract Cassia seed extract Shikimic acid Rotundine Nicotinamide Green coffee P.E. Rimonabant Neferine Glabridin Lotus Leaf Extract PU-ERHTEAP.E. Wolfberry extract Polysaccharides 15% UV Hawthorn NUCIFERINE O-METHYLISOCORYDINE IODOMETHYLATE 7-hydroxyglaucine

(-)-nucipherine

(r)-1,2-dimethoxyaporphine

1,2-dimethoxy-6a-beta-aporphin

4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-

Nuciferine 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

satis indigotica fort Extract

Lotus Leaf Extract Nuciferin

2%, 3%, 4%, 5%, 50%, 98% Lotus Leaf Extract Powder Nuciferine

Nuciferine, 98%, from Lotus Leaf

professional manufacturer Nuciferine 475-83-2

Nuciferine 475-83-2

radix bupleuri P.E

5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-g)quinolin(r)-4h-dibenzo(d

l-5,6-dimethoxyaporphine

l-nuciferine

nuciferin

NUCIFERINE

1,2-Dimethoxy-6aβ-aporphine

Sanjoinine E

(6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline

1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

(R)-Nuciferine

D-(-)-Nuciferine

1,2-Dimethoxy-6αβ-aporphine

VLT 049

Sanjoinine

(R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

Lotus Leaf Extract Powder Nuciferine

NUCIFERINE USP/EP/BP

Lotus leaf alkali

Nuciferi

fettuccine

lotus leaf extract lotusine

NUCIFERINE (lotusleaf extract)

Louts Leaf Extract

Nuciferine-RM

Nuciferine, 10 mM in DMSO

(6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

Nuciferine - Bio-X ?

Extractum Nelumbinis nuciferae folium

475-83-2

standardized herbal extract

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

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