Uses
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NUCIFERINE

Uses
Product Name
NUCIFERINE
CAS No.
475-83-2
Chemical Name
NUCIFERINE
Synonyms
nuciferin;6a;VLT 049;Nuciferi;NUCIFERINE;Sanjoinine;fettuccine;l-nuciferine;Sanjoinine E;Nuciferine-RM
CBNumber
CB4384597
Molecular Formula
C19H21NO2
Formula Weight
295.38
MOL File
475-83-2.mol
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NUCIFERINE Property

Melting point:
165.5°C
Boiling point:
437.06°C (rough estimate)
Density 
1.1156 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
2-8°C
solubility 
DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
pka
7.87±0.20(Predicted)
form 
powder
color 
white to beige
optical activity
[α]/D -145 to -165°, c = 0.5 in ethanol
LogP
2.357 (est)
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Safety

Safety Statements 
24/25
RIDADR 
UN 1544PSN1 6.1 / PGIII
HS Code 
29389090
Toxicity
LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2230
Product name
Nuciferine
Purity
≥98% (HPLC)
Packaging
5mg
Price
$63.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2230
Product name
Nuciferine
Purity
≥98% (HPLC)
Packaging
25mg
Price
$193
Updated
2024/03/01
TCI Chemical
Product number
N1170
Product name
Nuciferine
Packaging
250MG
Price
$672
Updated
2024/03/01
TCI Chemical
Product number
N1170
Product name
Nuciferine
Packaging
50MG
Price
$275
Updated
2021/12/16
Sigma-Aldrich
Product number
PHL83282
Product name
Nuciferine
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$514
Updated
2024/03/01
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NUCIFERINE Chemical Properties,Usage,Production

Uses

The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments.

Description

Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] 22D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.).

Uses

Nuciferin is an drug candidate for the treatment of obesity-related diseases. It is not well studied and its pharmacokinetics in vivo have not been fully investigated.

Safety Profile

Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.

References

Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963)

NUCIFERINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NUCIFERINE Suppliers

Americas 1 China 311 Europe 1 India 5 Japan 1 The Netherlands 1 United Kingdom 6 United States 20 USA 1 Global 347
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View Lastest Price from NUCIFERINE manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
NUCIFERINE 475-83-2
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
≥98%
Supply Ability
20tons
Release date
2024-01-04
BINBO BIOLOGICAL CO.,LTD
Product
Nuciferine 475-83-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000 kg
Release date
2024-04-11
Hebei Yanxi Chemical Co., Ltd.
Product
NUCIFERINE 475-83-2
Price
US $0.00/kg
Min. Order
0.5kg
Purity
0.99
Supply Ability
100kg
Release date
2023-09-22

475-83-2, NUCIFERINERelated Search:

PEPPERMINT Tea polyphenol Kidney Bean Extract Cassia seed extract Shikimic acid Rotundine Nicotinamide Green coffee P.E. Rimonabant Neferine Glabridin Lotus Leaf Extract PU-ERHTEAP.E. Wolfberry extract Polysaccharides 15% UV Hawthorn NUCIFERINE O-METHYLISOCORYDINE IODOMETHYLATE 7-hydroxyglaucine

  • (-)-nucipherine
  • (r)-1,2-dimethoxyaporphine
  • 1,2-dimethoxy-6a-beta-aporphin
  • 6a
  • 4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-
  • Nuciferine 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
  • satis indigotica fort Extract
  • Lotus Leaf Extract Nuciferin
  • 2%, 3%, 4%, 5%, 50%, 98% Lotus Leaf Extract Powder Nuciferine
  • Nuciferine, 98%, from Lotus Leaf
  • professional manufacturer Nuciferine 475-83-2
  • Nuciferine 475-83-2
  • radix bupleuri P.E
  • 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-g)quinolin(r)-4h-dibenzo(d
  • l-5,6-dimethoxyaporphine
  • l-nuciferine
  • nuciferin
  • NUCIFERINE
  • 1,2-Dimethoxy-6aβ-aporphine
  • Sanjoinine E
  • (6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
  • 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
  • (R)-Nuciferine
  • D-(-)-Nuciferine
  • 1,2-Dimethoxy-6αβ-aporphine
  • VLT 049
  • Sanjoinine
  • (R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
  • Lotus Leaf Extract Powder Nuciferine
  • NUCIFERINE USP/EP/BP
  • Lotus leaf alkali
  • Nuciferi
  • fettuccine
  • lotus leaf extract lotusine
  • NUCIFERINE (lotusleaf extract)
  • Louts Leaf Extract
  • 1,2-Dimethoxy-6αβ-aporphine
  • Nuciferine-RM
  • 475-83-2
  • standardized herbal extract
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • Miscellaneous Natural Products