H-THR-NH2 HCL

Product Name: H-THR-NH2 HCL
CAS No.: 33209-01-7
Chemical Name: H-THR-NH2 HCL
Synonyms: Thr-NH2;THR-NH2HCL;L-Thr-NH2·HCl;H-THR-NH2·HCL;H-THR-NH2 HCL;H-L-THR-NH2 HCL;THREONINE-NH2 HCL;L-ThreonineamideHCl;L-Threoninamide HCl;H-Thr-Nh2 Hydrochloride
CBNumber: CB4394914
Molecular Formula: C4H11ClN2O2
Formula Weight: 154.59
MOL File: 33209-01-7.mol

More

Less

H-THR-NH2 HCL Property

storage temp.: Inert atmosphere,Room Temperature
Appearance: White to off-white Solid
optical activity: Consistent with structure

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: T405550
Product name: L-ThreonineAmideHydrochloride
Packaging: 1g
Price: $55
Updated: 2021/12/16

TRC

Product number: T405550
Product name: L-ThreonineAmideHydrochloride
Packaging: 10g
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 291114
Product name: L-Threonine amide hydrochloride
Packaging: 2g
Price: $370
Updated: 2021/12/16

Usbiological

Product number: 453449
Product name: L-Threonine Amide Hydrochloride
Packaging: 1g
Price: $319
Updated: 2021/12/16

Matrix Scientific

Product number: 086061
Product name: (2S,3R)-2-Amino-3-hydroxybutanamide hydrochloride
Purity: 95%
Packaging: 1g
Price: $157
Updated: 2021/12/16

More

Less

H-THR-NH2 HCL Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

L-Threonine Amide Hydrochloride is used as a reagent in the synthesis of N-monosubstituted [(pyridin-2-yl)methyl]amine and [(pyrimidin-4-yl)methyl]amine derivatives as transient receptor potential cation channel 3 (TRPV3) modulators.

Synthesis

49705-98-8

33209-01-7

The general procedure for the synthesis of (2S,3R)-2-amino-3-hydroxy-1-oxobutan-2-yl)carbamic acid benzyl ester from (2S,3R)-1-amino-3-hydroxybutyramide hydrochloride is as follows: dissolve N-Cbz-ThrNH2 (504 g, 2 mol) in methanol, followed by addition of 10% Pd/C catalyst (50.4 g, 10 wt%) . The resulting suspension was stirred in hydrogen (1.0 MPa) atmosphere for 12 h at room temperature. Upon completion of the reaction, the Pd/C catalyst was removed by filtration, and the filtrate was evaporated under vacuum to obtain a crude product in the form of a yellow oil. This crude product was redissolved in 3 L of acetone, and HCl solution dissolved in isopropanol (500 mL) was added slowly at 0-5 °C while stirring. The precipitated white solid was collected by filtration and dried under high vacuum (45 °C, 0.1 MPa) to give the final target product 1b 289 g (93.5% yield). The product was analyzed by 1H-NMR (400 MHz, D2O) showing δ 4.15 (p, J = 6.1 Hz, 1H), 3.86 (d, J = 5.2 Hz, 1H), 1.25 (d, J = 6.5 Hz, 3H); and 13C-NMR (101 MHz, D2O) analysis showing δ 170.25, 66.04, 58.40, 18.80. HRMS (ESI-TOF+) analysis showed m/z ([M + H]+) calculated value of 119.0815 (corresponding to C14H11N2O2 + H+) and measured value of 119.0817.

References

[1] Molecules, 2018, vol. 23, # 5,

H-THR-NH2 HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

H-THR-NH2 HCL Suppliers

China 82 Germany 5 India 8 Japan 4 South Korea 1 Switzerland 2 United Kingdom 6 United States 22 Global 130

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 915
Advantage: 55

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

More

Less

View Lastest Price from H-THR-NH2 HCL manufacturers

Career Henan Chemical Co

Product: (2S,3R)-2-amino-3-hydroxybutanamide,hydrochloride 33209-01-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons
Release date: 2020-02-14

33209-01-7, H-THR-NH2 HCLRelated Search:

Mideplanin BLEOMYCIN A5 HYDROCHLORIDE H-THR-NH2 HCL chloropolysporin B helvecardin A PHOMOPSIN A ENDURACIDIN A H-TYR-THR-NH2 HCL H-THR(TBU)-GLY-OET HCL chloropolysporin C BLEOMYCIN A2, HYDROCHLORIDE [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT H-ARG-THR-NH2 2 HCL helvecardin B orienticin B MZ-4-71 decaplanin orienticin A

H-THR-NH2·HCL

[R-(R*,S*)]-2-amino-3-hydroxybutyramide monohydrochloride

L-Threoninamide monohydrochloride

L-Threoninamide HCl

THR-NH2HCL

L-ThreonineamideHCl

H-Thr-NH2·HCl L-threonine aMide hydrochloride

(2S,3R)-2-Amino-3-hydroxybutanamide hydrochloride

2-Amino-3-hydroxy-(2S,3R)butanamide monohydrochloride

L-Thr-NH2·HCl

-2-Amino-3-hydroxybutanamide hydrochloride

L-Threonine amide hydrochloride≥ 98%(HPLC)

H-THR-NH2 HCL

H-L-THR-NH2 HCL

L-Threonine amide. HCl salt

H-Thr-Nh2 Hydrochloride

L-THREONINE AMIDE HYDROCHLORIDE

L-THREONINAMIDE HYDROCHLORIDE

THREONINE-NH2 HCL

THREONINE AMIDE HYDROCHLORIDE

TIANFU CHEM--H-THR-NH2 HCL

Thr-NH2

33209-01-7

Threonine [Thr, T]

Amino Acids