ChemicalBook > CAS DataBase List > [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
- Product Name
- [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
- CAS No.
- 102805-45-8
- Chemical Name
- [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
- Synonyms
- Cpl-vip;[(4CL)DPHE6,LEU17] VIP;[d-p-cl-phe6, leu17]-vip;Vip, 4-cl-Phe(6)-Leu(17)-;(p-Chloro-D-Phe?,Leu1?)-VIP;(P-CHLORO-D-PHE6,LEU17)-VIP;6-(4-Chlorophenylalanyl)-17-leucine-vip;[PCL-D-PHE6, LEU17]VIP, HUMAN, PORCINE, RAT;(p-Chloro-D-Phe6,Leu17)-VIP (huMan, Mouse, rat);[P-CHLORO-D-PHE6,LEU17]-VIP, HUMAN, PORCINE, RAT
- CBNumber
- CB5267712
- Molecular Formula
- C148H239ClN44O42
- Formula Weight
- 3342.2
- MOL File
- 102805-45-8.mol
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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Property
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- Powder
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- V4380
- Product name
- [D-p-Cl-Phe6, Leu17]-Vasoactive Intestinal Peptide human, porcine, rat
- Purity
- ≥97% (HPLC)
- Packaging
- 1mg
- Price
- $758
- Updated
- 2023/06/20
Tocris
- Product number
- 3054
- Product name
- [D-p-Cl-Phe6,Leu17]-VIP
- Packaging
- 1
- Price
- $303
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5369
- Product name
- [D-p-Cl-Phe6,Leu17]-VIP
- Packaging
- 1mg
- Price
- $440
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC109522
- Product name
- (p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 trifluoroacetate salt
- Packaging
- 2mg
- Price
- $486
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC109522
- Product name
- (p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 trifluoroacetate salt
- Packaging
- 500ug
- Price
- $165
- Updated
- 2021/12/16
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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Chemical Properties,Usage,Production
Uses
[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF receptors[1][2][3].
Biochem/physiol Actions
VIP receptor antagonist
storage
Store at -20°C
References
[1] Pozo D, et, al. Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur J Pharmacol. 1997 Mar 5; 321(3): 379-86. DOI:10.1016/s0014-2999(96)00966-1
[2] Pandol SJ, et, al. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol. 1986 Apr; 250 (4 Pt 1): G553-7. DOI:10.1152/ajpgi.1986.250.4.G553
[3] Messmer B, et, al. Regulation of exocrine pancreatic secretion by cerebral TRH and CGRP: role of VIP, muscarinic, and adrenergic pathways. Am J Physiol. 1993 Feb; 264(2 Pt 1): G237-42. DOI:10.1152/ajpgi.1993.264.2.G237
[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Preparation Products And Raw materials
Raw materials
Preparation Products
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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Suppliers
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View Lastest Price from [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- (p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)|[4ClDPhe6,Leu17] VIP 102805-45-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10
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