ChemicalBook > CAS DataBase List > [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT

[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT

Product Name
[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
CAS No.
102805-45-8
Chemical Name
[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
Synonyms
Cpl-vip;[(4CL)DPHE6,LEU17] VIP;[d-p-cl-phe6, leu17]-vip;Vip, 4-cl-Phe(6)-Leu(17)-;(p-Chloro-D-Phe?,Leu1?)-VIP;(P-CHLORO-D-PHE6,LEU17)-VIP;6-(4-Chlorophenylalanyl)-17-leucine-vip;[PCL-D-PHE6, LEU17]VIP, HUMAN, PORCINE, RAT;(p-Chloro-D-Phe6,Leu17)-VIP (huMan, Mouse, rat);[P-CHLORO-D-PHE6,LEU17]-VIP, HUMAN, PORCINE, RAT
CBNumber
CB5267712
Molecular Formula
C148H239ClN44O42
Formula Weight
3342.2
MOL File
102805-45-8.mol
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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Property

Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
-20°C
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
V4380
Product name
[D-p-Cl-Phe6, Leu17]-Vasoactive Intestinal Peptide human, porcine, rat
Purity
≥97% (HPLC)
Packaging
1mg
Price
$758
Updated
2023/06/20
Tocris
Product number
3054
Product name
[D-p-Cl-Phe6,Leu17]-VIP
Packaging
1
Price
$303
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109522
Product name
(p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 trifluoroacetate salt
Packaging
500ug
Price
$165
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109522
Product name
(p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 trifluoroacetate salt
Packaging
1mg
Price
$286
Updated
2021/12/16
ApexBio Technology
Product number
B5369
Product name
[D-p-Cl-Phe6,Leu17]-VIP
Packaging
1mg
Price
$440
Updated
2021/12/16
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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Chemical Properties,Usage,Production

Uses

[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF receptors[1][2][3].

Biochem/physiol Actions

VIP receptor antagonist

storage

Store at -20°C

References

[1] Pozo D, et, al. Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur J Pharmacol. 1997 Mar 5; 321(3): 379-86. DOI:10.1016/s0014-2999(96)00966-1
[2] Pandol SJ, et, al. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol. 1986 Apr; 250 (4 Pt 1): G553-7. DOI:10.1152/ajpgi.1986.250.4.G553
[3] Messmer B, et, al. Regulation of exocrine pancreatic secretion by cerebral TRH and CGRP: role of VIP, muscarinic, and adrenergic pathways. Am J Physiol. 1993 Feb; 264(2 Pt 1): G237-42. DOI:10.1152/ajpgi.1993.264.2.G237

[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Preparation Products And Raw materials

Raw materials

Preparation Products

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[D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT Suppliers

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View Lastest Price from [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)|[4ClDPhe6,Leu17] VIP 102805-45-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

102805-45-8, [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RATRelated Search:


  • H-HIS-SER-ASP-ALA-VAL-D-PHE(4-CL)-THR-ASP-ASN-TYR-THR-ARG-LEU-ARG-LYS-GLN-LEU-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-ILE-LEU-ASN-NH2
  • HIS-SER-ASP-ALA-VAL-PCL-D-PHE-THR-ASP-ASN-TYR-THR-ARG-LEU-ARG-LYS-GLN-LEU-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-ILE-LEU-ASN-NH2
  • (D-PHE(4-CL)6,LEU17)-VIP (HUMAN,BOVINE, PORCINE, RAT)
  • [D-P-CL-PHE6,LEU17]-VASOACTIVE INTESTINAL PEPTIDE
  • [D-P-CL-PHE6,LEU17]-VASOACTIVE INTESTINAL PEPTIDE HUMAN
  • [D-P-CL-PHE(6),LEU(17)]-VASOACTIVE INTESTINAL PEPTIDE HUMAN, PORCINE, RAT
  • (D-P-CL-PHE6,LEU17)-VASOACTIVE*INTESTINA L PEPTIDE H
  • [d-p-cl-phe6,leu17]-vasoactiveintestinalpeptidefromprocine
  • [d-p-cl-phe6, leu17]-vip
  • vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-
  • L-His-L-Ser-L-Asp-L-Ala-L-Val-4-Chloro-D-Phe-L-Thr-L-Asp-L-Asn-L-Tyr-L-Thr-L-Arg-L-Leu-L-Arg-L-Lys-L-Gln-L-Leu-L-Ala-L-Val-L-Lys-L-Lys-L-Tyr-L-Leu-L-Asn-L-Ser-L-Ile-L-Leu-L-Asn-NH2
  • HIS-SER-ASP-ALA-VAL-(PCL)DPHE-THR-ASP-ASN-TYR-THR-ARG-LEU-ARG-LYS-GLN-LEU-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-ILE-LEU-ASN-NH2
  • HIS-SER-ASP-ALA-VAL-PCLDPHE-THR-ASP-ASN-TYR-THR-ARG-LEU-ARG-LYS-GLN-LEU-ALA-VAL-LYS-LYS-TYR-LEU-ASN-SER-ILE-LEU-ASN-NH2 [HSDAV-PCLDPHE-TDNYTRLRKQLAVKKYLNSILN-NH2]
  • 6-(4-Chloro-Phe)-17-Leu-vasoactive intestinal peptide
  • 6-(4-Chlorophenylalanyl)-17-leucine-vip
  • Cpl-vip
  • Vasoactive intestinal octacosapeptide (pig), 6-(4-chloro-D-phenylalanine)-17-L-leucine-
  • Vasoactive intestinal peptide, 4-chlorophenylalanyl(6)-leucine(17)-
  • (p-Chloro-D-Phe?,Leu1?)-VIP
  • (p-Chloro-D-Phe6,Leu17)-VIP (human, mouse, rat) trifluoroacetate salt H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 trifluoroacetate salt
  • Vip, 4-cl-Phe(6)-Leu(17)-
  • (p-Chloro-D-Phe6,Leu17)-VIP (huMan, Mouse, rat)
  • H-His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
  • (p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)|[4ClDPhe6,Leu17] VIP
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  • [P-CHLORO-D-PHE6,LEU17]-VIP, HUMAN, PORCINE, RAT
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  • [(4CL)DPHE6,LEU17] VASOACTIVE INTESTINAL PEPTIDE
  • [(4CL)DPHE6,LEU17] VIP
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  • D-p-Cl-Phe6, Leu17]-Vasoactive Intestinal Peptide human, porcine, rat >=97% (HPLC)
  • (P-CHLORO-D-PHE6,LEU17)-VIP
  • (p-Chloro-D-Phe?,Leu??)-VIP (human, mouse, rat) trifluoroacetate salt
  • VIP receptor antagonist (Human, Bovine, Porcine, Rat)
  • [<sc>D</sc>-<i>p</i>-Cl-Phe<sup>6</sup>, Leu<sup>17</sup>]-Vasoactive Intestinal Peptide human, porcine, rat
  • 102805-45-8
  • C148H239ClN44O42
  • C148H239N44O42Cl
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • Peptides
  • Vasoactive Intestinal Peptides