2-AMINO-3-NITRO-5-FLUOROPYRIDINE
- Product Name
- 2-AMINO-3-NITRO-5-FLUOROPYRIDINE
- CAS No.
- 212268-12-7
- Chemical Name
- 2-AMINO-3-NITRO-5-FLUOROPYRIDINE
- Synonyms
- 5-Fluoro-3-nitro-2-pyridinamine;5-fluoro-3-nitropyridin-2-amine;2-AMINO-5-FLUORO-3-NITROPYRIDINE;2-AMINO-3-NITRO-5-FLUOROPYRIDINE;2-Pyridinamine, 5-fluoro-3-nitro-;5-Fluoro-3-nitropyridin-2-ylamine;2-Amino-5-fluoro-3-nitropyridine,98%;2-Amino-5-fluoro-3-nitropyridine 98%;2-Pyridinamine,5-fluoro-3-nitro-(9CI);2-Amino-3-nitro-5-fluoropyridine≥ 99% (HPLC)
- CBNumber
- CB4396756
- Molecular Formula
- C5H4FN3O2
- Formula Weight
- 157.1
- MOL File
- 212268-12-7.mol
2-AMINO-3-NITRO-5-FLUOROPYRIDINE Property
- Boiling point:
- 290.1±35.0 °C(Predicted)
- Density
- 1.555±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Crystalline
- pka
- 0.12±0.49(Predicted)
- color
- Orange
- CAS DataBase Reference
- 212268-12-7(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A615115
- Product name
- 2-Amino-3-nitro-5-fluoropyridine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J95842
- Product name
- 2-Amino-3-nitro-5-fluoropyridine
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC445028
- Product name
- 2-Amino-5-fluoro-3-nitropyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $67
- Updated
- 2021/12/16
- Product number
- FA55569
- Product name
- 2-Amino-3-nitro-5-fluoropyridine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-W008428
- Product name
- 2-Amino-3-nitro-5-fluoropyridine
- Purity
- 99.59%
- Packaging
- 5g
- Price
- $180
- Updated
- 2021/12/16
2-AMINO-3-NITRO-5-FLUOROPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Off-white to yellow solid
Synthesis
21717-96-4
212268-12-7
Example 2.4 Synthesis of 2-amino-5-fluoro-3-nitropyridine: 2-amino-5-fluoropyridine (8.6 g, 77 mmol) was dissolved in concentrated hydrochloric acid. A mixed acid solution consisting of nitric acid (3.25 ml, 77 mmol) and sulfuric acid (40 ml) was added slowly and dropwise (over 30 min) at 3°C. The reaction mixture was first stirred at room temperature for 1 hour, then warmed up to 55°C and continued stirring for 1 hour. Upon completion of the reaction, the mixture was decanted into ice water, neutralized with 10 M sodium hydroxide solution and subsequently extracted with dichloromethane. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified twice by silica gel column chromatography, the first time using methanol: dichloromethane (1:20) as eluent and the second time using ether: petroleum ether (1:1) as eluent, resulting in 2-amino-3-nitro-5-fluoropyridine (0.44 g, 3.6% yield).1H-NMR (300 MHz, CDCl3): δ 6.65 (broad single peak, 2H), δ 8.20 (double peak, 1H), 8.35 (single peak, 1H).
References
[1] Patent: US6265415, 2001, B1
[2] Patent: EP2471792, 2012, A1. Location in patent: Page/Page column 39
2-AMINO-3-NITRO-5-FLUOROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-3-NITRO-5-FLUOROPYRIDINE manufacturers
- Product
- 2-AMINO-3-NITRO-5-FLUOROPYRIDINE 212268-12-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 2-AMINO-3-NITRO-5-FLUOROPYRIDINE 212268-12-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01