3-Amino-5-fluoropyridine
- Product Name
- 3-Amino-5-fluoropyridine
- CAS No.
- 210169-05-4
- Chemical Name
- 3-Amino-5-fluoropyridine
- Synonyms
- 5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%;3-Amino-5-fluoropyridine >
- CBNumber
- CB6767921
- Molecular Formula
- C5H5FN2
- Formula Weight
- 112.11
- MOL File
- 210169-05-4.mol
3-Amino-5-fluoropyridine Property
- Melting point:
- 86°C
- Boiling point:
- 232.7±20.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- pka
- 3.74±0.20(Predicted)
- color
- Light orange to Yellow to Green
- CAS DataBase Reference
- 210169-05-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22-36/37/38-22
- Safety Statements
- 26-36-36/37
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 732176
- Product name
- 3-Amino-5-fluoropyridine
- Packaging
- 500mg
- Price
- $131
- Updated
- 2023/06/20
- Product number
- A2753
- Product name
- 3-Amino-5-fluoropyridine
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- A2753
- Product name
- 3-Amino-5-fluoropyridine
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $211
- Updated
- 2024/03/01
- Product number
- H34111
- Product name
- 3-Amino-5-fluoropyridine, 98%
- Packaging
- 5g
- Price
- $243.65
- Updated
- 2024/03/01
- Product number
- H34111
- Product name
- 3-Amino-5-fluoropyridine, 98%
- Packaging
- 1g
- Price
- $61.1
- Updated
- 2021/12/16
3-Amino-5-fluoropyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow Crystal
Uses
3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.
Application
Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.
Preparation
synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.
3-Amino-5-fluoropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-5-fluoropyridine manufacturers
- Product
- 3-AMINO-5-FLUOROPYRIDINE 210169-05-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 3-Amino-5-fluoropyridine 210169-05-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- follow your request
- Release date
- 2023-06-01
- Product
- 5-fluoropyridin-3-amine 210169-05-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.7%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18