3-Amino-5-fluoropyridine

ChemicalBook > CAS DataBase List > 3-Amino-5-fluoropyridine

3-Amino-5-fluoropyridine

Product Name: 3-Amino-5-fluoropyridine
CAS No.: 210169-05-4
Chemical Name: 3-Amino-5-fluoropyridine
Synonyms: 5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%;3-Amino-5-fluoropyridine >
CBNumber: CB6767921
Molecular Formula: C5H5FN2
Formula Weight: 112.11
MOL File: 210169-05-4.mol

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3-Amino-5-fluoropyridine Property

Melting point:: 86°C
Boiling point:: 232.7±20.0 °C(Predicted)
Density: 1.257±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 3.74±0.20(Predicted)
color: Light orange to Yellow to Green
CAS DataBase Reference: 210169-05-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 26-36-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 732176
Product name: 3-Amino-5-fluoropyridine
Packaging: 500mg
Price: $131
Updated: 2023/06/20

TCI Chemical

Product number: A2753
Product name: 3-Amino-5-fluoropyridine
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $62
Updated: 2024/03/01

TCI Chemical

Product number: A2753
Product name: 3-Amino-5-fluoropyridine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $211
Updated: 2024/03/01

Alfa Aesar

Product number: H34111
Product name: 3-Amino-5-fluoropyridine, 98%
Packaging: 5g
Price: $243.65
Updated: 2024/03/01

Alfa Aesar

Product number: H34111
Product name: 3-Amino-5-fluoropyridine, 98%
Packaging: 1g
Price: $61.1
Updated: 2021/12/16

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3-Amino-5-fluoropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Crystal

Uses

3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.

Application

Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.

Preparation

synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.

3-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials

4-Methylmorpholine Hexane Isoamyl nitrite Ethanol Ammonium formate Diphenylphosphoryl azide Benzyl alcohol 5-Fluoronicotinic acid Palladium Fluoroboric acid Diethyl ether 1,2-Dichloroethane 5-Methylpyridin-3-amine Hydrochloric acid Methanol

Preparation Products

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3-Amino-5-fluoropyridine Suppliers

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View Lastest Price from 3-Amino-5-fluoropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-AMINO-5-FLUOROPYRIDINE 210169-05-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

Changzhou waston chemical technology Co.,Ltd

Product: 3-Amino-5-fluoropyridine 210169-05-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: follow your request
Release date: 2023-06-01

Honest Joy Holdings Limited

Product: 5-fluoropyridin-3-amine 210169-05-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.7%
Supply Ability: 100 tons
Release date: 2022-02-18

210169-05-4, 3-Amino-5-fluoropyridineRelated Search:

5-Fluoro-2-oxindole 4-BROMO-5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 2-BROMO-5-FLUORO-3-NITROPYRIDINE 2-AMINO-3-NITRO-5-FLUOROPYRIDINE 3-FLUORO-4-NITROPYRIDINE-N-OXIDE 2-CHLORO-5-FLUORO-3-NITROPYRIDINE 3-Fluoro-4-nitropyridine 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE 3-Amino-5-fluoropyridine 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE 4-(DIMETHYLAMINO)-2,3,5,6-TETRAFLUOROPYRIDINE 5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE 4-Amino-2-fluoropyridine97%,4-AMINO-2-FLUOROPYRIDINE 2-Amino-5-fluoropyridine 6-FLUORO-3,4-PYRIDINEDIAMINE 2-Amino-3-fluoropyridine97%,2-AMINO-3-FLUOROPYRIDINE 98%,2-AMINO-3-FLUOROPYRIDINE BOC-5-AMINO-2-FLUOROPYRIDINE,N-Boc-5-amino-2-fluoropyridine

3-AMINO-5-FLUOROPYRIDINE

3-Pyridinamine,5-fluoro-(9CI)

3-AMINO-5-FLUOROPYRIDINE 97%

5-Fluoropyridin-3-amine

5-Fluoropyridin-3-ylamine

3-Amine-5-fluoro-pyridin

3-AMine-5-fluoro-pyridine

3-PyridinaMine,5-fluoro-

3-aMino -5-fluorine pyridine

5-Fluoro-3-pyridinamine

3-AMINO-5-FLUOROPYRIDINE(RS20014327)

3-Amino-5-fluoropyridine &gt

3-AMINO-5-FLUOROPYRIDINE ISO 9001：2015 REACH

210169-05-4

Fluorine series

Building Blocks

C5 to C6

Chemical Synthesis

Fluorinated Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Heterocyclic Fluorinated Building Blocks

Other Fluorinated Heterocycles

Pyridine series

Pyridines

Boronic Acid

PYRIDINE

AMINEPRIMARY

HALIDE