ChemicalBook > CAS DataBase List > 2-AMINO-3-NITRO-5-FLUOROPYRIDINE

2-AMINO-3-NITRO-5-FLUOROPYRIDINE

Product Name
2-AMINO-3-NITRO-5-FLUOROPYRIDINE
CAS No.
212268-12-7
Chemical Name
2-AMINO-3-NITRO-5-FLUOROPYRIDINE
Synonyms
5-Fluoro-3-nitro-2-pyridinamine;5-fluoro-3-nitropyridin-2-amine;2-AMINO-5-FLUORO-3-NITROPYRIDINE;2-AMINO-3-NITRO-5-FLUOROPYRIDINE;2-Pyridinamine, 5-fluoro-3-nitro-;5-Fluoro-3-nitropyridin-2-ylamine;2-Amino-5-fluoro-3-nitropyridine,98%;2-Amino-5-fluoro-3-nitropyridine 98%;2-Pyridinamine,5-fluoro-3-nitro-(9CI);2-Amino-3-nitro-5-fluoropyridine≥ 99% (HPLC)
CBNumber
CB4396756
Molecular Formula
C5H4FN3O2
Formula Weight
157.1
MOL File
212268-12-7.mol
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2-AMINO-3-NITRO-5-FLUOROPYRIDINE Property

Boiling point:
290.1±35.0 °C(Predicted)
Density 
1.555±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
Crystalline
pka
0.12±0.49(Predicted)
color 
Orange
CAS DataBase Reference
212268-12-7(CAS DataBase Reference)
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A615115
Product name
2-Amino-3-nitro-5-fluoropyridine
Packaging
100mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J95842
Product name
2-Amino-3-nitro-5-fluoropyridine
Packaging
250mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
PC445028
Product name
2-Amino-5-fluoro-3-nitropyridine
Purity
98%
Packaging
1g
Price
$67
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA55569
Product name
2-Amino-3-nitro-5-fluoropyridine
Packaging
500mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-W008428
Product name
2-Amino-3-nitro-5-fluoropyridine
Purity
99.59%
Packaging
5g
Price
$180
Updated
2021/12/16
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2-AMINO-3-NITRO-5-FLUOROPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white to yellow solid

Synthesis

21717-96-4

212268-12-7

Example 2.4 Synthesis of 2-amino-5-fluoro-3-nitropyridine: 2-amino-5-fluoropyridine (8.6 g, 77 mmol) was dissolved in concentrated hydrochloric acid. A mixed acid solution consisting of nitric acid (3.25 ml, 77 mmol) and sulfuric acid (40 ml) was added slowly and dropwise (over 30 min) at 3°C. The reaction mixture was first stirred at room temperature for 1 hour, then warmed up to 55°C and continued stirring for 1 hour. Upon completion of the reaction, the mixture was decanted into ice water, neutralized with 10 M sodium hydroxide solution and subsequently extracted with dichloromethane. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified twice by silica gel column chromatography, the first time using methanol: dichloromethane (1:20) as eluent and the second time using ether: petroleum ether (1:1) as eluent, resulting in 2-amino-3-nitro-5-fluoropyridine (0.44 g, 3.6% yield).1H-NMR (300 MHz, CDCl3): δ 6.65 (broad single peak, 2H), δ 8.20 (double peak, 1H), 8.35 (single peak, 1H).

References

[1] Patent: US6265415, 2001, B1
[2] Patent: EP2471792, 2012, A1. Location in patent: Page/Page column 39

2-AMINO-3-NITRO-5-FLUOROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3-NITRO-5-FLUOROPYRIDINE Suppliers

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View Lastest Price from 2-AMINO-3-NITRO-5-FLUOROPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-AMINO-3-NITRO-5-FLUOROPYRIDINE 212268-12-7
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
Career Henan Chemical Co
Product
2-AMINO-3-NITRO-5-FLUOROPYRIDINE 212268-12-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

212268-12-7, 2-AMINO-3-NITRO-5-FLUOROPYRIDINERelated Search:


  • 2-AMINO-3-NITRO-5-FLUOROPYRIDINE
  • 2-AMINO-5-FLUORO-3-NITROPYRIDINE
  • 2-Pyridinamine,5-fluoro-3-nitro-(9CI)
  • 2-Amino-5-fluoro-3-nitropyridine 98%
  • 5-fluoro-3-nitropyridin-2-amine
  • 5-Fluoro-3-nitro-2-pyridinamine
  • 2-Amino-3-nitro-5-fluoropyridine≥ 99% (HPLC)
  • 2-Pyridinamine, 5-fluoro-3-nitro-
  • 2-Amino-5-fluoro-3-nitropyridine,98%
  • 2-AMINO-3-NITRO-5-FLUOROPYRIDINE ISO 9001:2015 REACH
  • 5-Fluoro-3-nitropyridin-2-ylamine
  • 212268-12-7
  • C5H4FN2O2
  • C5H4FN3O2
  • C5H4FN3O
  • Fluorine series
  • Pyridines
  • Boronic Acid
  • HALIDE
  • Pyridine