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10-PROPOXY-DECANOIC ACID

Product Name
10-PROPOXY-DECANOIC ACID
CAS No.
119290-12-9
Chemical Name
10-PROPOXY-DECANOIC ACID
Synonyms
O-11;O11,O 11;10-PROPOXY-DECANOIC ACID;11-OXATETRADECANOIC ACID;Decanoic acid, 10-propoxy-;HSRAJJQTYQHRSA-UHFFFAOYSA-N;10-(propoxy)decanoyl-coenzyme A
CBNumber
CB4408954
Molecular Formula
C13H26O3
Formula Weight
230.34
MOL File
119290-12-9.mol
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10-PROPOXY-DECANOIC ACID Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
90510
Product name
O-11
Purity
≥98%
Packaging
1mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
90510
Product name
O-11
Purity
≥98%
Packaging
5mg
Price
$210
Updated
2024/03/01
Cayman Chemical
Product number
90510
Product name
O-11
Purity
≥98%
Packaging
10mg
Price
$371
Updated
2024/03/01
AK Scientific
Product number
1138AH
Product name
10-Propoxy-decanoicacid
Packaging
10mg
Price
$510
Updated
2021/12/16
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10-PROPOXY-DECANOIC ACID Chemical Properties,Usage,Production

Definition

ChEBI: 10-propoxydecanoic acid is a medium-chain fatty acid.

Biological Activity

O-11 is an analog of the fully saturated, 14-carbon fatty acid myristic acid, in which the methylene group at position 11 is replaced with oxygen. It is highly effective and selective at killing Trypanosoma brucei, the protozoan parasite responsible for African sleeping sickness, exhibiting an LD50 of less than 1 μM in a cell culture assay.1,2 The toxic effects of O-11 appear to be caused by its ability to inhibit the incorporation of a single myristate into the GPI anchor of the variant surface glycoprotein (VSG), a protein critical for evading the host immune response.1 O-11 exhibits essentially no anti-fungal activity when assayed using C. neoformans, but does have a minor inhibitory effect on HIV-1 replication in T-lymphocytes.3

References

1.Doering, T.L., Raper, J., Buxbaum, L.U., et al.An analog of myristic acid with selective toxicity for African trypanosomesScience2521851-1854(1991) 2.Doering, T.L., Lu, T., Werbovetz, K.A., et al.Toxicity of myristic acid analogs toward African trypanosomesProceedings of the National Academy of Sciences of the United States of America919735-9739(1994) 3.Langner, C.A., Lodge, J.K., Travis, S.J., et al.4-Oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus IThe Journal of Biological Chemisty267(24)17159-17169(1992)

10-PROPOXY-DECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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10-PROPOXY-DECANOIC ACID Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58

119290-12-9, 10-PROPOXY-DECANOIC ACIDRelated Search:


  • 11-OXATETRADECANOIC ACID
  • 10-PROPOXY-DECANOIC ACID
  • O-11
  • 10-(propoxy)decanoyl-coenzyme A
  • HSRAJJQTYQHRSA-UHFFFAOYSA-N
  • Decanoic acid, 10-propoxy-
  • O11,O 11
  • 119290-12-9