ChemicalBook > CAS DataBase List > 3,5-Lutidine

3,5-Lutidine

Product Name
3,5-Lutidine
CAS No.
591-22-0
Chemical Name
3,5-Lutidine
Synonyms
35L;Lutidine,98%;3,5-LUTIDINE;3,5-Lutidine>3,5-Lutidine,99%;3,5-LUTIDINE, 98+%;3,5-Dimetylpyridine;Nicotine Impurity 6;3,5-dimethyl-pyridin;3,5-DIMETHYLPYRIDINE
CBNumber
CB4412061
Molecular Formula
C7H9N
Formula Weight
107.15
MOL File
591-22-0.mol
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3,5-Lutidine Property

Melting point:
-9 °C (lit.)
Boiling point:
169-170 °C (lit.)
Density 
0.939 g/mL at 25 °C (lit.)
vapor pressure 
1.5 mm Hg ( 20 °C)
refractive index 
n20/D 1.504(lit.)
Flash point:
128 °F
storage temp. 
2-8°C
form 
Liquid
pka
6.15(at 25℃)
color 
Clear yellow
Water Solubility 
33 g/L (20 ºC)
Sensitive 
Hygroscopic
BRN 
105682
InChIKey
HWWYDZCSSYKIAD-UHFFFAOYSA-N
LogP
1.780
CAS DataBase Reference
591-22-0(CAS DataBase Reference)
NIST Chemistry Reference
Pyridine, 3,5-dimethyl-(591-22-0)
EPA Substance Registry System
3,5-Dimethylpyridine (591-22-0)
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Safety

Hazard Codes 
Xn,F,Xi,T
Risk Statements 
10-20/21/22-36/37/38-41-34-23/25-21
Safety Statements 
16-26-36-36/37-45-36/37/39
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
8
Hazard Note 
Irritant/Flammable
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L4206
Product name
3,5-Lutidine
Purity
≥98%
Packaging
100ml
Price
$67.6
Updated
2024/03/01
TCI Chemical
Product number
L0068
Product name
3,5-Lutidine
Purity
>98.0%(GC)
Packaging
25mL
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
L0068
Product name
3,5-Lutidine
Purity
>98.0%(GC)
Packaging
500mL
Price
$175
Updated
2024/03/01
Alfa Aesar
Product number
A14877
Product name
3,5-Lutidine, 99%
Packaging
25ml
Price
$23.65
Updated
2024/03/01
Alfa Aesar
Product number
A14877
Product name
3,5-Lutidine, 99%
Packaging
100ml
Price
$40.65
Updated
2024/03/01
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3,5-Lutidine Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

3,5-Lutidine is a reactant used in the synthesis of phthalazine and pyrazine compounds, as well as other pharmaceuticals.

Synthesis Reference(s)

Synthesis, p. 573, 1994 DOI: 10.1055/s-1994-25526

Flammability and Explosibility

Flammable

Purification Methods

Dry 3,5-lutidine with sodium and fractionally distil it through a Todd column (p 11) packed with glass helices. Dissolve (100mL) in dilute HCl (1:4) and steam distil this until 1L of distillate is collected. Excess conc NaOH is added to the residue which is again steam distilled. The base is extracted from the distillate, using diethyl ether. The extract is dried over K2CO3, and distilled. It is then fractionally crystallised by partial freezing. The hydrochloride has m 229o(sublimes at 190-231o), and the picrate has m 242-243o(dec, from H2O), 249-250o(dec, from AcOH). [Beilstein 20 II 161, 20 III/IV 2788, 20/6 V 60.]

3,5-Lutidine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Lutidine Suppliers

CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
PARAGOS
Tel
--
Fax
--
Email
info@paragos.com
Country
Germany
ProdList
6371
Advantage
39
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
Merck Schuchardt OHG
Tel
--
Fax
--
Email
schuchardt-vertrieb@merck.de
Country
Germany
ProdList
5827
Advantage
74
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View Lastest Price from 3,5-Lutidine manufacturers

Dideu Industries Group Limited
Product
3,5-Lutidine 591-22-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-25
Longyan Tianhua Biological Technology Co., Ltd
Product
3,5-Lutidine 591-22-0
Price
US $5.00/Kg/Bag
Min. Order
10Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-10-29
Career Henan Chemical Co
Product
3,5-Lutidine 591-22-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
as request
Release date
2018-12-21

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