3,4-Lutidine

3,4-Lutidine Property

Melting point:

-12 °C

Boiling point:

163-164 °C(lit.)

Density 

0.954 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.511(lit.)

Flash point:

129 °F

storage temp. 

Flammables area

pka

6.46(at 25℃)

form 

clear liquid

color 

yellow

Water Solubility 

52 g/L (20 ºC)

Sensitive 

Hygroscopic

BRN 

106583

Henry's Law Constant

2.7×10⁰ mol/(m³Pa) at 25℃, Andon et al. (1954)

Dielectric constant

11.470000000000001

LogP

1.749 (est)

CAS DataBase Reference

583-58-4(CAS DataBase Reference)

NIST Chemistry Reference

Pyridine, 3,4-dimethyl-(583-58-4)

EPA Substance Registry System

3,4-Dimethylpyridine (583-58-4)

Safety

Hazard Codes 

T,F,Xi

Risk Statements 

10-23/24/25-36/37/38-24-20/22-23/24-22

Safety Statements 

16-26-36/37/39-45

RIDADR 

UN 2929 6.1/PG 2

WGK Germany 

3

RTECS 

OK9800000

TSCA 

TSCA listed

HazardClass 

6.1

PackingGroup 

II

HS Code 

29333999

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H310Fatal in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

3,4-Lutidine Chemical Properties,Usage,Production

Chemical Properties

clear yellow to brownish liquid

Uses

3,4-Lutidine is used as an intermediate in the preparation of active pharmaceutical ingredient. It is used to prepare tetrhydropyridine derivatives by reduction.

Safety Profile

Poison by skin contact. Moderately toxic by ingestion and inhalation. When heated to decomposition it emits toxic fumes of NOx.