ChemicalBook > CAS DataBase List > 5-Methyl-3-phenylisoxazole-4-carbonyl chloride

5-Methyl-3-phenylisoxazole-4-carbonyl chloride

Product Name
5-Methyl-3-phenylisoxazole-4-carbonyl chloride
CAS No.
16883-16-2
Chemical Name
5-Methyl-3-phenylisoxazole-4-carbonyl chloride
Synonyms
PMIC CHLORIDE;3-PHENYL-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE;BUTTPARK 43\57-11;Idarubicin Impurity 23;5-Methyl-3-Phenylisoxazole-4-C;5-Methyl-3-phenyl-4-isoxazolyl chloride;5-METHYL-3-PHENYL-4-CHLOROCARBONYL ISOXAZOLE;5-methyl-3-phenyl-4-isoxazolecarbonylchlorid;Methyl-3-phenylisoxazole-4-carbonyl chloride;5-Methyl-3-phenyl-4-isoxazolecarbonylchloride
CBNumber
CB4412218
Molecular Formula
C11H8ClNO2
Formula Weight
221.64
MOL File
16883-16-2.mol
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5-Methyl-3-phenylisoxazole-4-carbonyl chloride Property

Melting point:
24 °C
Boiling point:
115-117 °C(Press: 3 Torr)
Density 
1.27
vapor pressure 
0.007Pa at 25℃
Flash point:
>100
solubility 
soluble in Methanol
form 
powder to lump
pka
-4.78±0.50(Predicted)
color 
White to Light yellow
Water Solubility 
701.8mg/L at 25℃
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C11H8ClNO2/c1-7-9(11(12)14)10(13-15-7)8-5-3-2-4-6-8/h2-6H,1H3
InChIKey
HXEVQMXCHCDPSO-UHFFFAOYSA-N
SMILES
C(Cl)(C1=C(C)ON=C1C1=CC=CC=C1)=O
LogP
1.97 at 25℃
CAS DataBase Reference
16883-16-2(CAS DataBase Reference)
EPA Substance Registry System
4-Isoxazolecarbonyl chloride, 5-methyl-3-phenyl- (16883-16-2)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34-36
Safety Statements 
26-36/37/39-45-26/36/37/39/45-20
RIDADR 
UN3261
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2996
Product name
5-Methyl-3-phenylisoxazole-4-carbonyl Chloride
Packaging
1G
Price
$41
Updated
2025/07/31
TCI Chemical
Product number
M2996
Product name
5-Methyl-3-phenylisoxazole-4-carbonyl Chloride
Packaging
5G
Price
$116
Updated
2025/07/31
Usbiological
Product number
283696
Product name
5-Methyl-3-phenylisoxazole-4-carbonyl chloride
Packaging
1g
Price
$419
Updated
2021/12/16
AK Scientific
Product number
Y7785
Product name
5-Methyl-3-phenylisoxazole-4-carbonyl Chloride
Packaging
5g
Price
$216
Updated
2021/12/16
SynQuest Laboratories
Product number
4H16-5-Z5
Product name
5-Methyl-3-phenylisoxazole-4-carbonyl chloride
Packaging
1g
Price
$112
Updated
2021/12/16
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5-Methyl-3-phenylisoxazole-4-carbonyl chloride Chemical Properties,Usage,Production

Chemical Properties

Crystallizes. Melting point 184°C.

Uses

Used as Intermediate of oxacillin sodium.

Flammability and Explosibility

Not classified

Synthesis

Benzaldehyde and hydroxylamine hydrochloride are oximeated under alkaline conditions to generate benzoxime, which is then chlorinated with chlorine to give benzoxime chloride. It is combined with ethyl acetoacetate to hydrolyze and chlorinated to obtain 5-Methyl-3-phenylisoxazole-4-carbonyl chloride.

5-Methyl-3-phenylisoxazole-4-carbonyl chloride Preparation Products And Raw materials

Raw materials

5-Methyl-3-phenylisoxazole-4-carboxylic acid Phosphorus pentachloride Hydroxylamine hydrochloride

Preparation Products

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5-Methyl-3-phenylisoxazole-4-carbonyl chloride Suppliers

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View Lastest Price from 5-Methyl-3-phenylisoxazole-4-carbonyl chloride manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
5-Methyl-3-phenylisoxazole-4-carbonyl chloride 16883-16-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-04-15
Hebei Yanxi Chemical Co., Ltd.
Product
5-Methyl-3-phenylisoxazole-4-carbonyl chloride 16883-16-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%GC
Supply Ability
20tons
Release date
2023-09-13
Shaanxi Dideu New Materials Co. Ltd
Product
5-Methyl-3-phenylisoxazole-4-carbonyl chloride 16883-16-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-07

16883-16-2, 5-Methyl-3-phenylisoxazole-4-carbonyl chlorideRelated Search:

Dichloromethylphenylsilane o-Toluoyl chloride Methacryloyl chloride Bensulfuron methyl 3,5,5-Trimethylhexanoyl chloride Methyl salicylate Kresoxim-methyl p-Toluoyl chloride Isobutyryl chloride 5-Methyl-1H-benzotriazole Methyltriphenylphosphonium bromide PYRAZOPHOS CARBONYL SULFIDE METSULFURON METHYL Methylparaben Sulfamethoxazole Thiophanate-methyl Methyl

  • 5-methyl-3-phenyl-1,2-oxazole-4-carbonylchloride
  • 5-methyl-3-phenyl-4-isoxazolecarbonylchlorid
  • 5-Methyl-3-phenyl-4-isoxazolecarbonylchloride
  • PMIC CHLORIDE
  • 3-PHENYL-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE
  • 5-METHYL-3-PHENYLISOXAZOLE-4-CARBONYL CHLORIDE
  • 5-METHYL-3-PHENYL-4-CHLOROCARBONYL ISOXAZOLE
  • 5-Methyl-3-Phenyl-Isoxazol-4-Carboxylicacid Chloride
  • BUTTPARK 43\57-11
  • 5-METHYL-3-PHENYL-4-CHLOROCARBONYLICISOXAZOLE ACID
  • 5-Methyl-3-Phenylisoxazole-4-C
  • 5-Methyl-3-phenylisoxazole-4-carboxylic acid chloride
  • 5-methyl-3-phenyl-4-isoxazolecarboxylic acid chloride
  • 5-Methyl-3-phenyl-1,2-oxazole-4-carbonyl chloride, 4-(Chlorocarbonyl)-5-methyl-3-phenylisoxazole
  • 4-Isoxazolecarbonylchloride, 5-Methyl-3-phenyl-
  • 5-methyl-3-phenylisoxazole-4-carboxylic chloride
  • 5-Methyl-3-phenyl-4-isoxazolyl chloride
  • Methyl-3-phenylisoxazole-4-carbonyl chloride
  • Idarubicin Impurity 23
  • 16883-16-2
  • C11H8CINO2
  • C11H8ClNO2
  • Oxazole&Isoxazole