2-Benzofurancarboxylic acid ethyl ester

Product Name: 2-Benzofurancarboxylic acid ethyl ester
CAS No.: 3199-61-9
Chemical Name: 2-Benzofurancarboxylic acid ethyl ester
Synonyms: Ethyl CouMarilate;RARECHEM AL BI 0556;Ethyl 2-benzofurancarboxylate;ethyl benzofuran-2-carboxylate;Ethyl 1-benzofuran-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate 97%;BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER;BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER;2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER
CBNumber: CB4414494
Molecular Formula: C11H10O3
Formula Weight: 190.2
MOL File: 3199-61-9.mol

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2-Benzofurancarboxylic acid ethyl ester Property

Melting point:: 166-170℃
Boiling point:: 105°/0.1mm
Density: 1.1656
refractive index: 1.5640 (estimate)
Flash point:: >110℃
storage temp.: 2-8°C
CAS DataBase Reference: 3199-61-9(CAS DataBase Reference)

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Safety

Hazard Codes: T
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2932190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 763632
Product name: Ethyl benzofuran-2-carboxylate
Purity: 97%
Packaging: 1g
Price: $30.2
Updated: 2023/06/20

TRC

Product number: E904900
Product name: EthylCoumarilate
Packaging: 2.5g
Price: $160
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H23-1-X1
Product name: Ethylbenzo[b]furan-2-carboxylate
Purity: 97%
Packaging: 1g
Price: $108
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB33202
Product name: Benzofuran-2-carboxylic acid ethyl ester
Packaging: 500mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: N531
Product name: Benzofuran-2-carboxylicacidethylester
Packaging: 10g
Price: $134
Updated: 2021/12/16

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2-Benzofurancarboxylic acid ethyl ester Chemical Properties,Usage,Production

Uses

Ethyl Coumarilate has been used as a reactant for the preparation of benzofuropyridines that have a high affinity for the α2-adrenoceptor.

Preparation

Synthesis of ethyl benzofuran-2-carboxylate: Salicylaldehyde (20.0 mL, 0.164 mol) and diethyl bromomalonate (40.0 mL, 0.168 mol) in ethyl methyl ketone (40.0 mL, 0.555 mol) was treated with anhydrous potassium carbonate (20.0 g,0.869 mol). The reaction mixture was refluxed for 18 h on steam bath. Ethyl methyl ketone was distilled off under reduced pressure and the residue formed was dissolved in 400 mL of water and cooled in an ice-bath. It was acidified with dil H2SO4. The product formed was extracted with 25 mL portion of solvent ether twice and the extract was washed with sodium bicarbonate solution. It was dried over calcium chloride. Solvent was removed and the residue ethyl benzofuran-2-carboxylate was dried.

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 6315, 1986 DOI: 10.1016/S0040-4039(00)87796-5

2-Benzofurancarboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Sodium hydride Potassium carbonate 2-Butanone Salicylaldehyde Diethyl ether Dimethyl sulfoxide Diethyl malonate Cupric bromide

Preparation Products

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2-Benzofurancarboxylic acid ethyl ester Suppliers

China 76 France 1 Germany 3 India 2 Switzerland 1 United Kingdom 9 United States 14 Global 106

Carbosynth

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Hawks Scientific Ltd

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MOLEKULA Ltd.

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Manchester Organics

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CARBONE SCIENTIFIC CO.,LTD

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UK GREEN SCIENTIFIC CO.,LIMITED

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Eurolabs Limited

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View Lastest Price from 2-Benzofurancarboxylic acid ethyl ester manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Benzofurancarboxylic acid ethyl ester 3199-61-9
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-09

Career Henan Chemical Co

Product: 2-Benzofurancarboxylic acid ethyl ester 3199-61-9
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-09

3199-61-9, 2-Benzofurancarboxylic acid ethyl esterRelated Search:

BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER

BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER

Ethyl benzo[b]furan-2-carboxylate 97%

RARECHEM AL BI 0556

2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER

ethyl benzofuran-2-carboxylate

Ethyl 2-benzofurancarboxylate

2-(Ethoxycarbonyl)benzo[b]furan, Ethyl 1-benzofuran-2-carboxylate

Ethyl CouMarilate

Ethyl 1-benzofuran-2-carboxylate

1-isobenzofurancarboxylic acid ethyl ester

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3199-61-9

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