4-(4-Methylpiperazino)benzylamine

Product Name: 4-(4-Methylpiperazino)benzylamine
CAS No.: 216144-45-5
Chemical Name: 4-(4-Methylpiperazino)benzylamine
Synonyms: AKOS B022037;BUTTPARK 98\50-54;ART-CHEM-BB B022037;4-(4-Methylpiperazino)benzylam;4-(4-Methylpiperazin-1-yl)Benz;4-(4-METHYLPIPERAZINO)BENZYLAMINE;4-(4-Methylpiperazino)benzylamine90%;4-(4-Methylpiperazino)benzylamine 90%;4-(4-Methylpiperazin-1-yl)benzylamine;4-(4-Methyl-1-piperazinyl)benzylamine
CBNumber: CB4420929
Molecular Formula: C12H19N3
Formula Weight: 205.3
MOL File: 216144-45-5.mol

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4-(4-Methylpiperazino)benzylamine Property

Boiling point:: 122-124/0.05mm
Density: 1.065±0.06 g/cm3(Predicted)
storage temp.: Store at Room Tem.
pka: 10.40±0.10(Predicted)
CAS DataBase Reference: 216144-45-5(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 36/37/38-34
Safety Statements: 26-36/37/39-45
Hazard Note: Corrosive
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: M331593
Product name: 4-(4-Methylpiperazino)benzylamine
Packaging: 5g
Price: $60
Updated: 2021/12/16

Oakwood

Product number: 033776
Product name: 4-(4-Methylpiperazino)benzylamine
Purity: 98%
Packaging: 1g
Price: $20
Updated: 2021/12/16

AK Scientific

Product number: J51368
Product name: 4-(4-Methylpiperazino)benzylamine
Packaging: 5g
Price: $95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0024567
Product name: 4-(4-METHYLPIPERAZINO)BENZYLAMINE
Purity: 95.00%
Packaging: 1G
Price: $193.2
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-1-M7
Product name: 4-(4-Methylpiperazin-1-yl)benzylamine
Purity: 95.0%
Packaging: 5G
Price: $224
Updated: 2021/12/16

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4-(4-Methylpiperazino)benzylamine Chemical Properties,Usage,Production

Synthesis

34334-28-6

216144-45-5

General procedure for the synthesis of 4-(4-methyl-1-piperazinyl)benzylamine from 4-(4-methylpiperazin-1-yl)benzonitrile: Sodium borohydride (10 eq.) was added to a solution of 4-(4-methylpiperazin-1-yl)benzonitrile (1 eq.) and cobalt chloride hexahydrate (2.1 eq.). The reaction mixture was stirred for 5 hours and then filtered through a pad of diatomaceous earth. The organic phase was concentrated under reduced pressure. The yellow oil obtained was purified by rapid chromatography on silica gel (dichloromethane: methanol = 8:2) to afford the target compound 4-(4-methyl-1-piperazinyl)benzylamine as a white solid in 50% yield.1H NMR (400 MHz, methanol-d4): δ (ppm) 2.42 (s, 3H); 2.74 (t, J=8Hz, 4H); 3.17 (t. J=8Hz, 4H); 4.43 (s, 2H); 6.89 (d, J=8Hz, 2H); 7.18 (d, J=8Hz, 2H). Elemental analysis (C12H19N3) calculated values: C, 70.20; H, 9.33; N, 20.47; measured values: C, 70.10; H, 9.13; N, 20.27.

References

[1] Tetrahedron Letters, 2013, vol. 54, # 38, p. 5204 - 5206
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 26, p. 8261 - 8269
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 12, p. 5293 - 5305
[4] ACS Medicinal Chemistry Letters, 2018, vol. 9, # 7, p. 741 - 745

4-(4-Methylpiperazino)benzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Methylpiperazino)benzylamine Suppliers

Belgium 1 China 75 Germany 5 India 2 Russia 1 Ukraine 1 United Kingdom 7 United States 14 Global 106

J & K SCIENTIFIC LTD.

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216144-45-5, 4-(4-Methylpiperazino)benzylamineRelated Search:

Trimethoprim Benzylamine Phenoxybenzamine hydrochloride Dibenzylamine 1-Methylpiperazine 4-Fluorobenzylamine 4-Hydroxybenzylamine TERT-BUTYL 4-[4-(AMINOMETHYL)PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE 3-(4-METHYLPIPERAZINO)BENZYLAMINE 2-(4-METHYLPIPERAZINO)BENZYLAMINE 3-AMINO-4-(4-METHYL-PIPERAZIN-1-YL)-BENZAMIDE 1-BOC-4-(4-CARBAMIMIDOYL-PHENYL)-PIPERAZINE TERT-BUTYL 4-[4-[AMINO(HYDROXYIMINO)METHYL]PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE 4-(4-Methylpiperazino)benzylamine TERT-BUTYL 4-[4-(([(4-METHYLPHENYL)SULFONYL]AMINO)METHYL)PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE TERT-BUTYL 4-[4-(([(4,5-DIBROMO-1H-PYRROL-2-YL)CARBONYL]AMINO)METHYL)PHENYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE TERT-BUTYL 4-(4-([(4-CHLOROBENZOYL)AMINO]METHYL)PHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE TERT-BUTYL 4-(4-([(3-METHOXYBENZOYL)AMINO]METHYL)PHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE

4-(4-Methyl-1-piperazinyl)benzylamine

4-(4-Methylpiperazin-1-yl)benzylamine

BUTTPARK 98\50-54

ART-CHEM-BB B022037

AKOS B022037

4-(4-METHYLPIPERAZINO)BENZYLAMINE

4-(4-Methylpiperazin-1-yl)Benz

4-(4-Methylpiperazino)benzylam

4-(4-Methylpiperazino)benzylamine 90%

4-(4-Methylpiperazino)benzylamine90%

4-(4-Methylpiperazin-1-yl)benzylamine 90%

(4-(4-methylpiperazin-1-yl)phenyl)methanamine

4-(4-Methylpiperazin-1-yl)benzylamine 95+%

[4-(4-Methylpiperazin-1-yl)phenyl]methylamine

Benzenemethanamine, 4-(4-methyl-1-piperazinyl)-

216144-45-5

216155-45-5

Phenyls & Phenyl-Het

Piperazines

Piperazidine intermediates

Aminomethyl's

Phenyls & Phenyl-Het

Piperaizine