(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- Product Name
- (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- CAS No.
- 101152-94-7
- Chemical Name
- (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- Synonyms
- IXEL;F 2207;TOLEDOMIN;Dalcipran;cis-(+-)-d;MIDALCIPRAN;MLNACIPRAM HCL;Milnacipran HCI;Chiral Reagents;MILNACIPRAN HCL
- CBNumber
- CB4423243
- Molecular Formula
- C15H23ClN2O
- Formula Weight
- 282.81
- MOL File
- 101152-94-7.mol
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Property
- Melting point:
- 179-1810C
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- H2O: 19 mg/mL
- form
- solid
- color
- white
- Merck
- 14,6194
- CAS DataBase Reference
- 101152-94-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,T,F
- Risk Statements
- 22-39/23/24/25-23/24/25-11
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- GZ1014010
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29242990
- Toxicity
- LD50 orally in mice: 237 mg/kg (Bonnaud)
N-Bromosuccinimide Price
- Product number
- M-145
- Product name
- Milnacipran hydrochloride solution
- Purity
- 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $213
- Updated
- 2024/03/01
- Product number
- M1318
- Product name
- Milnacipran hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 10mg
- Price
- $242
- Updated
- 2024/03/01
- Product number
- M1318
- Product name
- Milnacipran hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 50mg
- Price
- $526.2
- Updated
- 2024/03/01
- Product number
- M2133
- Product name
- Milnacipran Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 50mg
- Price
- $18
- Updated
- 2024/03/01
- Product number
- M2133
- Product name
- Milnacipran Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 500mg
- Price
- $94
- Updated
- 2024/03/01
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Uses
antibacterial
Uses
Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
Definition
ChEBI: Milnacipran hydrochloride is a member of acetamides.
General Description
Milnacipran, sold under the brand names Savella?, Ixel?, Dalcipran?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biological Activity
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Biochem/physiol Actions
Serotonin and norepinephrine reuptake inhibitor (SNRI)
storage
+4°C
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Suppliers
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View Lastest Price from (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride manufacturers
- Product
- Milnacipran hydrochloride solution 101152-94-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Milnacipran hydrochloride solution 101152-94-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
- Product
- Milnacipran Hydrochloride 101152-94-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26