E-64C
- Product Name
- E-64C
- CAS No.
- 76684-89-4
- Chemical Name
- E-64C
- Synonyms
- E-64C;NSC 694279;E-64c, EP 475;Loxistatin acid;anecarboxylicacid;ep475(enzymeinhibitor);Loxistatin Acid (E-64C);Inhibitorforthiolprotease;NSC 694279 Loxistatin Acid;E-64-c Loxistatin acid NSC 694279
- CBNumber
- CB4425580
- Molecular Formula
- C15H26N2O5
- Formula Weight
- 314.38
- MOL File
- 76684-89-4.mol
E-64C Property
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- ≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
- form
- White to off-white solid
- color
- White to off-white
- InChIKey
- SCMSYZJDIQPSDI-SRVKXCTJSA-N
Safety
- WGK Germany
- 3
- RTECS
- RR0404200
- HS Code
- 29241990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 10007964
- Product name
- E-64c
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 10007964
- Product name
- E-64c
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $270
- Updated
- 2024/03/01
- Product number
- 10007964
- Product name
- E-64c
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $477
- Updated
- 2024/03/01
- Product number
- 10007964
- Product name
- E-64c
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $1041
- Updated
- 2024/03/01
- Product number
- E100495
- Product name
- E-64c
- Packaging
- 25mg
- Price
- $875
- Updated
- 2021/12/16
E-64C Chemical Properties,Usage,Production
Description
E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.
Uses
E-64c is a cysteine protease inhibitor used for detecting autophagy in plants.
Definition
ChEBI: E-64c is a leucine derivative.
target
cathepsins B
E-64C Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from E-64C manufacturers
- Product
- E-64C;NSC 694279 Loxistatin Acid 76684-89-4
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 1kg;10kg; 25kg
- Release date
- 2020-01-07