ChemicalBook > CAS DataBase List > E-64C

E-64C

Product Name
E-64C
CAS No.
76684-89-4
Chemical Name
E-64C
Synonyms
E-64C;NSC 694279;E-64c, EP 475;Loxistatin acid;anecarboxylicacid;ep475(enzymeinhibitor);Loxistatin Acid (E-64C);Inhibitorforthiolprotease;NSC 694279 Loxistatin Acid;E-64-c Loxistatin acid NSC 694279
CBNumber
CB4425580
Molecular Formula
C15H26N2O5
Formula Weight
314.38
MOL File
76684-89-4.mol
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E-64C Property

storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form 
White to off-white solid
color 
White to off-white
InChIKey
SCMSYZJDIQPSDI-SRVKXCTJSA-N
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Safety

WGK Germany 
3
RTECS 
RR0404200
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10007964
Product name
E-64c
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
10007964
Product name
E-64c
Purity
≥98%
Packaging
5mg
Price
$270
Updated
2024/03/01
Cayman Chemical
Product number
10007964
Product name
E-64c
Purity
≥98%
Packaging
10mg
Price
$477
Updated
2024/03/01
Cayman Chemical
Product number
10007964
Product name
E-64c
Purity
≥98%
Packaging
25mg
Price
$1041
Updated
2024/03/01
TRC
Product number
E100495
Product name
E-64c
Packaging
25mg
Price
$875
Updated
2021/12/16
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E-64C Chemical Properties,Usage,Production

Description

E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.

Uses

E-64c is a cysteine protease inhibitor used for detecting autophagy in plants.

Definition

ChEBI: E-64c is a leucine derivative.

target

cathepsins B

E-64C Preparation Products And Raw materials

Raw materials

Preparation Products

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E-64C Suppliers

China 92 France 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 16 USA 1 Global 115
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from E-64C manufacturers

Career Henan Chemical Co
Product
E-64C;NSC 694279 Loxistatin Acid 76684-89-4
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
1kg；10kg; 25kg
Release date
2020-01-07

76684-89-4, E-64CRelated Search:

2-Hydroxy-4-amino butanoic acid (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID BUTTPARK 37\11-64 GLYCIDAMIDE EST BUTTPARK 45\03-64 BUTTPARK 44\01-64 BUTTPARK 36\08-64 BUTTPARK 45\03-64 BUTTPARK 43\57-64 (2-amino-2-oxoethoxy)acetic acid E-64C (2-AMINO-ETHOXY)-ACETIC ACID 2(2-HYDROXYETHOXY)ACETAMIDE BUTTPARK 62\07-64 BUTTPARK 51\09-64 BUTTPARK 64\41-01 BUTTPARK 46\18-64

  • (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
  • (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
  • (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid
  • 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-
  • Loxistatin Acid (E-64C)
  • NSC 694279
  • E-64c, EP 475
  • (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
  • (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE
  • E-64C
  • L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE
  • E-64-c Loxistatin acid NSC 694279
  • (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir
  • (2s-(2-alpha,3-beta(r*)))-mino)carbonyl)
  • anecarboxylicacid
  • ep475(enzymeinhibitor)
  • oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a
  • (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL
  • Inhibitorforthiolprotease
  • (2S)-3β-[[[(S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2α-oxiranecarboxylic acid
  • (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid
  • Loxistatin acid
  • NSC 694279 Loxistatin Acid
  • NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C
  • 76684-89-4
  • BioChemical
  • Calpain
  • A to C
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Biochemicals and Reagents
  • Pepetides
  • Inhibitors
  • peptides