1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE
- Product Name
- 1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE
- CAS No.
- 91166-50-6
- Chemical Name
- 1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE
- Synonyms
- DK424;BIS(DIMETHYLAMINODIMETHYLSILYL)ETHANE;1,2-bis((diethylamino)dimethylsilyl)ethane;1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE;α,α'-Ethylenebis(N,N,α,α-tetramethylsilanamine);1,1'-ETHYLENEBIS(N,N,1,1-TETRAMETHYLSILANAMINE);1,1'-ETHYLENEBIS(N,N,1,1-TETRAMETHYLSILANAMIDE);[Protecting Reagent for Aromatic Primary Amines];1,2-Bis[(dimethylamino)dimethylsilyl]ethane 2,5-Bis(dimethylamino)-2,5-dimethyl-2,5-disilahexane
- CBNumber
- CB4429063
- Molecular Formula
- C10H28N2Si2
- Formula Weight
- 232.51
- MOL File
- 91166-50-6.mol
1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Property
- Boiling point:
- 101-103 °C13 mm Hg(lit.)
- Density
- 0.824 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.446(lit.)
- Flash point:
- 57 °F
- pka
- 10.31±0.70(Predicted)
- form
- clear liquid
- color
- Colorless to Almost colorless
- Specific Gravity
- 0.824
- Hydrolytic Sensitivity
- 8: reacts rapidly with moisture, water, protic solvents
- BRN
- 4366167
- CAS DataBase Reference
- 91166-50-6(CAS DataBase Reference)
Safety
- Hazard Codes
- F,C
- Risk Statements
- 11-34
- Safety Statements
- 16-26-36/37/39-45
- RIDADR
- UN 2924 3/PG 2
- WGK Germany
- 3
- F
- 10-21
- TSCA
- No
- HazardClass
- 3.1
- PackingGroup
- II
- HS Code
- 29319019
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B1773
- Product name
- 1,2-Bis[(dimethylamino)dimethylsilyl]ethane [Protecting Reagent for Aromatic Primary Amines]
- Purity
- >93.0%(GC)
- Packaging
- 5g
- Price
- $534
- Updated
- 2024/03/01
- Product number
- B447388
- Product name
- 1,1''-(1,2-Ethanediyl)bis[N,N,1,1-tetramethylsilanamine]
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B447388
- Product name
- 1,1''-(1,2-Ethanediyl)bis[N,N,1,1-tetramethylsilanamine]
- Packaging
- 5g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 40574
- Product name
- 1,2-Bis[(dimethylamino)dimethylsilyl]ethane,≥93%(GC)
- Purity
- ≥93%(GC)
- Packaging
- 5G
- Price
- $200.35
- Updated
- 2021/12/16
- Product number
- FB61077
- Product name
- 1,2-Bis[(dimethylamino)dimethylsilyl]ethane
- Packaging
- 5G
- Price
- $85
- Updated
- 2021/12/16
1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Chemical Properties,Usage,Production
Physical properties
bp 100–103°C/13 mmHg; d 0.824 g cm?3.
Uses
1,4-Bis(dimethylamino)-1,1,4,4-tetramethyldisilethylene is used as a reagent for the protection of primary amines with lower pKa
values, such as substituted anilines, as their tetramethyldisilylazacyclopentane
or Stabase adduct; precursor of tetramethyldisilylthiacyclopentane,
a sulfur transfer reagent.
The title reagent
is used for the preparation of Stabase derivatives of primary
amines, and is particularly useful for the protection of primary
aromatic amines with pKa values of 10–11. The protection of
substituted anilines is achieved by heating equimolar amounts of
the title compound and the anilines in the presence of zinc iodide
(0.5 mol %) under a slow stream of nitrogen at 140°C for 5 h. In
many cases the products can be purified by vacuum distillation.
Cleavage of the Stabase adducts to the corresponding primary
amines can be performed in ether in the presence of 2 equiv of
methanol and a small amount of p-toluenesulfonic acid monohydrate
(0.2 mol %). The tetramethyldisilylazacyclopentane or
Stabase adduct (3) is a particularly attractive protecting group due
to its ease of preparation, base stability, and facile removal (eq 1).
Preparation
the reagent is prepared as a colorless liquid in 90% yield by treating commercially available bis(chlorodimethylsilyl) ethane with 5 equiv of dimethylamine in ether at 0°C for 5 h.
1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Suppliers
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View Lastest Price from 1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE manufacturers
- Product
- 1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE 91166-50-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- customsie
- Release date
- 2018-08-20