ChemicalBook > CAS DataBase List > trans-3,4-Difluorocinnamic acid

trans-3,4-Difluorocinnamic acid

Product Name
trans-3,4-Difluorocinnamic acid
CAS No.
112897-97-9
Chemical Name
trans-3,4-Difluorocinnamic acid
Synonyms
AKOS 92715;RARECHEM BK HW 0122;TIMTEC-BB SBB006677;3,4-DIFLUOROCINNAMIC ACID;Phenylbutazone Impurity 35;rans-3,4-Difluorocinnamicaci;TRANS-3,4-DIFLUOROCINNAMIC ACID;trans-3,4-DifluorocinnamicAcid>trans-3,4-Difluorociamic acid,95%;trans-3,4-Difluorocinnamicacid97%
CBNumber
CB4452689
Molecular Formula
C9H6F2O2
Formula Weight
184.14
MOL File
112897-97-9.mol
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trans-3,4-Difluorocinnamic acid Property

Melting point:
194-196 °C(lit.)
Boiling point:
281.3±25.0 °C(Predicted)
Density 
1.3056 (estimate)
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
4.27±0.10(Predicted)
color 
White to Almost white
BRN 
7370322
CAS DataBase Reference
112897-97-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
290378
Product name
trans-3,4-Difluorocinnamic acid
Purity
95%
Packaging
5g
Price
$35.4
Updated
2023/06/20
TCI Chemical
Product number
D4161
Product name
trans-3,4-Difluorocinnamic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D4161
Product name
trans-3,4-Difluorocinnamic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$31
Updated
2024/03/01
Alfa Aesar
Product number
B20230
Product name
3,4-Difluorocinnamic acid, 97%
Packaging
1g
Price
$25.8
Updated
2021/12/16
Alfa Aesar
Product number
B20230
Product name
3,4-Difluorocinnamic acid, 97%
Packaging
5g
Price
$84.5
Updated
2021/12/16
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trans-3,4-Difluorocinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

trans-3,4-Difluorocinnamic Acid is a starting material in the preparation of Ticagrelor (T437700), which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

trans-3,4-Difluorocinnamic acid Preparation Products And Raw materials

Raw materials

Hexane Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Diethyl ether Ethyl acetate Sodium bicarbonate Dichloromethane tert-Butyl bromoacetate Sodium hydroxide Triphenylphosphine Magnesium sulfate 3,4-Difluorobenzaldehyde

Preparation Products

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trans-3,4-Difluorocinnamic acid Suppliers

Americas 1 Belgium 1 China 160 Europe 2 France 1 Germany 5 India 7 Italy 1 Japan 2 Switzerland 2 United Kingdom 21 United States 30 Global 233
Alchem Pharmtech,Inc.
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Aladdin Scientific
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Aceschem Inc.
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Synthonix Inc
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United States Biological
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Alfa Aesar
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INDOFINE Chemical Company, Inc.
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3B Scientific Corporation
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APAC Pharmaceutical, LLC
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American Custom Chemicals Corporation
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TimTec Corporation
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ChemPacific Corporation
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AK Scientific, Inc.
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View Lastest Price from trans-3,4-Difluorocinnamic acid manufacturers

Career Henan Chemical Co
Product
trans-3,4-Difluorocinnamic acid 112897-97-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10

112897-97-9, trans-3,4-Difluorocinnamic acidRelated Search:

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  • (E)-3,4-Difluorophenylacrylic acid, (2E)-3-(3,4-Difluorophenyl)prop-2-enoic acid
  • 3,4-DIFLUOROCINNAMIC ACID
  • AKOS 92715
  • TIMTEC-BB SBB006677
  • RARECHEM BK HW 0122
  • TRANS-3,4-DIFLUOROCINNAMIC ACID
  • trans-3,4-Difluorocinnamic acid 97%
  • trans-3,4-Difluorocinnamicacid97%
  • trans-3,4-Difluorociamic acid,95%
  • (E)-3-(3,4-difluorophenyl)-2-propenoate
  • trans-3,4-DifluorocinnamicAcid&gt
  • 2-Propenoic acid, 3-(3,4-difluorophenyl)-, (2E)-
  • rans-3,4-Difluorocinnamicaci
  • trans-3-(3,4-Difluorophenyl)acrylic Acid
  • trans-3,4-Difluorocinnamic acid USP/EP/BP
  • (E)-3-(3,4-difluorophenyl)prop-2-enoic acid
  • Phenylbutazone Impurity 35
  • <i>trans</i>-3,4-Difluorocinnamic acid
  • 112897-97-9
  • Organic Building Blocks
  • Building Blocks
  • C9
  • Carboxylic Acids
  • Carbonyl Compounds
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • Cinnamic acid
  • Miscellaneous
  • C9
  • Carbonyl Compounds
  • Carboxylic Acids
  • Fluoro-contained cinnamic acid series