ChemicalBook > CAS DataBase List > 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE

4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE

Product Name
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
CAS No.
164391-47-3
Chemical Name
4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
Synonyms
Zinc00005777;Immepip hydrobromide;IMMEPIP DIHYDROBROMIDE;4-(1H-Imidazol-5-ylmethyl)piperidine hydrobromide;4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE;Piperidine,4-(1H-imidazol-4-ylmethyl)-,dihydrobromide
CBNumber
CB4459345
Molecular Formula
C9H17Br2N3
Formula Weight
327.06
MOL File
164391-47-3.mol
More
Less

4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Property

Melting point:
234-235℃
storage temp. 
2-8°C
solubility 
H2O: 7 mg/mL at <40 °C
form 
solid
color 
light tan
Water Solubility 
Soluble to 100 mM in water
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I4034
Product name
Immepip dihydrobromide
Purity
≥97% (HPLC), powder
Packaging
10mg
Price
$204
Updated
2024/03/01
Sigma-Aldrich
Product number
I4034
Product name
Immepip dihydrobromide
Purity
≥97% (HPLC), powder
Packaging
50mg
Price
$646
Updated
2024/03/01
Cayman Chemical
Product number
29518
Product name
Immepip (hydrobromide)
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
29518
Product name
Immepip (hydrobromide)
Packaging
5mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
29518
Product name
Immepip (hydrobromide)
Packaging
10mg
Price
$160
Updated
2024/03/01
More
Less

4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Chemical Properties,Usage,Production

Description

Immepip is a histamine H3 receptor agonist (KI = 0.4 nM in SK-N-MC cell membranes expressing the human receptor). It is selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors, respectively (Kis = >16 μM for both) but also agonizes H4 receptors (KI = 9 nM in SK-N-MC cell membranes expressing the human receptor). Immepip (5 mg/kg, s.c.) decreases hypothalamic histamine release in anesthetized rats. It decreases flinching in the formalin test in rats when administered at doses of 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg.

Chemical Properties

Crystalline Solid

Uses

A selective nonchiral histamine H3 agonist.

Biological Activity

Potent histamine H 3 receptor agonist. Also binds to H 4 receptors (K i values are 0.4 and 9 nM at human recombinant H 3 and H 4 receptors respectively). Equipotent to or slightly more active than (R)- α -methylhistamine at H 3 receptors.

storage

Desiccate at RT

4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE Suppliers

Canada 1 China 39 Germany 3 India 1 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 11 USA 1 Global 61
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28809
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15084
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58

164391-47-3, 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDERelated Search:

4-(IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE

  • 4-(1H-IMIDAZOL-4-YLMETHYL)PIPERIDINE DIHYDROBROMIDE
  • IMMEPIP DIHYDROBROMIDE
  • Zinc00005777
  • 4-(1H-Imidazol-5-ylmethyl)piperidine hydrobromide
  • Immepip hydrobromide
  • Piperidine,4-(1H-imidazol-4-ylmethyl)-,dihydrobromide
  • 164391-47-3
  • C9H17Br2N3
  • C9H15N32HBr
  • 2BrHC9H15N3
  • Inhibitors
  • Histamine receptor